Роль полиморфизмов генов детоксикации ксенобиотиков в развитии миомы матки и эндометриоза

Ступко Екатерина Евгеньевна, Шенин Владимир Анатольевич, Колесникова Любовь Ильинична, Лабыгина Альбина Владимировна, Сутурина Лариса Викторовна
In: Сибирский медицинский журнал (Иркутск) · 2011 · vol. 104(5) · W1913358256
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This review examines the role of xenobiotic detoxification gene polymorphisms, specifically CYP1A1, CYP1A2, CYP3A5, CYP3A7, SULT1A1, and GSTP1, in the development of endometriosis and hysteromyoma in reproductive-aged women.

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Abstract

The review presents a comprehensive view on the pathogenesis of endometriosis and hysteromyoma in the women of reproductive age. The contribution of polymorphisms genes of detoxification of xenobiotics in the development of these pathologies was studied. The significant contribution of mutations in CYP1A1, CYP1A2, CYP3A5, CYP3A7, SULT1A1 and GSTP1 genes in development of endometriosis and hysteromyoma have been shown.

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endometriosis

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last seen: 2026-06-10T17:14:06.276822+00:00
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