Endometriosis fertility index and pregnancy outcomes of assisted reproductive technology

Endometriotic infertility is associated with poor pregnancy outcomes of assisted reproductive technology（ART） . The endometriosis fertility index（EFI）could predict pregnancy outcomes of non-ART after surgery for endometriosis. However, reports about EFI and postoperative pregnancy outcomes of ART are few, and their correlation remains controversial. Therefore, we investigated for this relationship in patients at our institution.

In this study, we included patients who underwent oocyte retrieval cycles of endometriotic infertility performed in our institution from January 2017 to December 2020. The patients’ background, surgical findings, and pregnancy outcomes were collected from medical records and retrospectively analyzed.

Patients with endometriosis surgery history underwent 84 cycles（surgical group）and those without underwent 83 cycles（non-surgical group） . In the surgical group, 22 cycles resulted in pregnancy（pregnancy group）and remaining 62 cycles did not（non-pregnancy group） . The EFI score of the pregnant group was significantly higher than that of the non-pregnant group（5 points vs. 3 points, p＝0.02） . A Higher EFI resulted in higher cumulative pregnancy rates.

EFI is positively correlated to the pregnancy outcomes of ART and hence a useful predictor of pregnancy outcomes.

Endometriotic infertility, EFI, ART, pregnancy

＊ Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine ＊＊ Sato Women‘s Clinic ＊＊＊ Yamagata Otemachi ART Clinic Michi Nishi ＊ , Isao Takehara ＊ , Saki Hine ＊ , Ai Sato ＊ , Fumihiro Nakamura ＊ , Risako Yamaguchi ＊ , Shota Horikawa ＊ , Tomomichi Ito ＊ , Nanako Nakai ＊ , Jun Matsukawa ＊ , Koki Matsuo ＊＊ , Jun Kawagoe ＊＊＊ , Manabu Seino ＊ , Tsuyoshi Ota ＊ , Satoru Nagase ＊ DOI 10.15022/0002000785