Intracavitary physiotherapy is not inferior to endometrial scratching in patients with recurrent implantation failure

In: Archives of Gynecology and Obstetrics · 2014 · vol. 291(1) , pp. 173–177 · doi:10.1007/s00404-014-3382-6 · PMID:25073778 · W2053403670
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Intracavitary physiotherapy showed no inferiority to endometrial scratching in improving implantation and clinical pregnancy rates for patients with recurrent implantation failure.

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This retrospective study investigated whether intracavitary physiotherapy is superior to endometrial scratching in 63 patients with recurrent implantation failure undergoing IVF/ICSI-embryo transfer, comparing three groups: intracavitary physiotherapy alone (n=20), both intracavitary physiotherapy and endometrial scratching (n=8), and endometrial scratching alone (n=35). The primary outcomes were implantation and clinical pregnancy rates, with pregnancy outcomes as secondary. No statistically significant differences were found between intracavitary physiotherapy and endometrial scratching or between the combined group and scratching alone for implantation, clinical pregnancy, or pregnancy outcomes (all P>0.05). The paper’s main limitation is that it is retrospective with small subgroup sizes, particularly the combined-treatment group. Relevance to endometriosis: the study focuses on recurrent implantation failure management and discusses uterine receptivity/local injury in a context that overlaps with implantation-related mechanisms implicated in endometriosis, though it does not explicitly study endometriosis patients.

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Abstract

Purpose To investigate whether intracavitary physiotherapy is superior to endometrial scratching in patients with recurrent implantation failure (RIF) after in vitro fertilization/intracytoplasmic sperm injection- embryo transfer (IVF/ICSI-ET) cycles.

Methods

According to the inclusion criteria defined by our hospital, 63 patients with RIF were included in the retrospective study. 20 patients who received intracavitary physiotherapy were classified into Group A, 8 patients with both intracavitary physiotherapy and endometrial scratching were into Group B, and 35 patients who underwent endometrial scratching were into Group C. The primary outcome measures were implantation and clinical pregnancy rates. The secondary outcome measure was pregnancy outcome.

Results

There were no statistical differences in implantation and clinical pregnancy rates between Groups A and C (29.41 vs 35.59 %, 45.00 vs 48.57 % respectively, P > 0.05), Groups B and C (36.36 vs 35.59 %, 50.00 vs 48.57 % respectively, P > 0.05). In addition, no statistical differences were discovered in pregnancy outcomes between Groups A and C (P > 0.05), Groups B and C (P > 0.05).

Conclusions

Intracavitary physiotherapy is not inferior to endometrial scratching on improving implantation and clinical pregnancy rates in patients with RIF after IVF/ICSI cycles. Similar content being viewed by others

References

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Rights and permissions About this article Cite this article Zhang, Q., Zhang, B., Yan, J. et al. Intracavitary physiotherapy is not inferior to endometrial scratching in patients with recurrent implantation failure. Arch Gynecol Obstet 291, 173–177 (2015). https://doi.org/10.1007/s00404-014-3382-6 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-014-3382-6

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