[Relationship between endometriosis fertility index and pregnancies after laparoscopic surgery in endometriosis-associated infertility]

Wei DM, Dai-min Wei, Qi Yu, Yu Q, Ai-Jun Sun, Sun AJ, Qin-jie Tian, Tian QJ, Rong Chen, Chen R, Cheng-yan Deng, Deng CY, Zheng-Yi Sun, Sun ZY, Zhen, Jing-ran Zhen, Zhen JR, Fang-Fang He, He FF
Zhonghua fu chan ke za zhi · 2011 · vol. 46(11) , pp. 806–8 · PMID:22333226 · W68627775
Observational OA: closed CC0 ⤵ 12 in-corpus citations
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This study found that the Endometriosis Fertility Index (EFI) score correlated with pregnancy rates in infertile patients after laparoscopic surgery, with higher EFI scores indicating better outcomes.

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Abstract

OBJECTIVE: To evaluate the relationship between endometriosis fertility index (EFI) and pregnancies after laparoscopic surgery in endometriosis-associated infertility. METHODS: From Jan. 2005 to Jan. 2010, medical documents of 350 infertile patients due to endometriosis undergoing laparoscopic surgery were studied retrospectively. Pregnancy outcomes were followed up by telephone. EFI was calculated by history factors, least function score and some aspects of the revised American Fertility Society (r-AFS) endometriosis stage. The cumulative pregnancy rate was calculated and compared by Kaplan-Meier survival analysis. RESULTS: Within 3 years after surgery, the cumulative pregnancy rates among patients with EFI score 8, 9, 10 were 62.5%, 69.8% and 81.1%, respectively. There was no significant difference in pregnancy rates among those three groups of patients (P = 0.24). The cumulative pregnancy rates among patients with EFI score 5, 6, 7 were 49.8%, 43.9% and 41.6%, respectively, which did not reach statistical difference (P = 0.83). The cumulative pregnancy rates of EFI score 8 - 10 was significantly higher than that of EFI score 5 - 7 (71.8% vs. 44.4%, P = 0.000). The patients with EFI score 0 - 4 was quite small with only 33 cases, among which 15 cases were pregnant. CONCLUSIONS: There is relationship between EFI and pregnancy in patients with endometriosis-associated infertility. EFI is meaningful to guide post-surgical treatment.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Endometriosis Endometriosis Endometriosis Female Female Fertility Fertility Humans Humans Infertility Infertility Infertility Infertility, Female Infertility, Female Laparoscopy Laparoscopy Pregnancy Pregnancy

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License: CC0 · commercial use OK