[Adenomyosis - diagnostic and therapeutic challenge].
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Adenomyosis, characterized by endometrial tissue within the myometrium causing uterine hypertrophy and potential abnormal bleeding or pain, is diagnosed via histology, ultrasound, or MRI and treated with hormonal therapy or fertility-sparing procedures.
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Abstract
In adenomyosis, endometrial glandular and stromal cells grow inside the myometrium, and form localized or diffusely expanding islets. Smooth muscle cells of the uterus surrounding the adenomyosis colonies become hypertrophic, which may lead to abnormal contractions of the uterine wall. Adenomyosis is an estrogen-dependent disease with abnormal uterine bleeding and dysmenorrhea as typical symptoms. The disease may even be asymptomate. The diagnosis is made by histologically or ultrasonic or MRI imaging. Adenomyosis can be treated with hormonal medications. Fertility-sparing radiologic and surgical techniques are also available.
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- europepmc
- last seen: 2026-08-01T06:07:04.264727+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:21:00.404924+00:00
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