Duodecim; laaketieteellinen aikakauskirja

Endometriosis affects about 2 to 10% of women in fertile age, It causes pain and infertility. In the ovaries, endometrios causes endometriomas. The disease may spread into the abdominal cavity and even result in ileus. Deep endometriomas ar…

Dysmenorrhea affects quality of life, but is often inadequately treated in teenagers. The mainstay of treatment is NSAID, which must be started pre-emptively and in adequate dose. If NSAID provides insufficient pain relief, or when contrace…

In adenomyosis, endometrial glandular and stromal cells grow inside the myometrium, and form localized or diffusely expanding islets. Smooth muscle cells of the uterus surrounding the adenomyosis colonies become hypertrophic, which may lead…

Endometriosis is an estrogen dependent disease, which causes chronic inflammation and may lead to pelvic pain and infertility. Women with endometriosis have a 1.5 to 2-fold risk for ovarian epithelial cancer. The risk is increased especiall…

Premature ovarian insufficiency (POI) is characterized by cessation of menstruation and elevated follicle stimulating hormone levels before the age of 40. Patients may have hypoestrogenic symptoms such as hot flushes. Most cases are idiopat…

BACKGROUND: In endometriosis endometrial tissue appears outside the uterine cavity causing dysmenorrhea, infertility, chronic abdominal pain and bowel symptoms. MATERIAL AND METHODS: The prevalence of bowel symptoms and the influence of su…

Ovulation problems, ovarian endometriosis and impaired sperm quality may be factors underlying infertility and possibly predisposing to cancer diseases. Infertility therapies utilize products that alter the hormonal balance and may in theor…

Early diagnosis of endometriosis is important for proper planning of the treatment. First-line treatment of moderate endometriosis is hormonal drug therapy, which should be long-standing. Surgery is needed, if pain symptoms cannot be contro…

Of women of reproductive age, 6 to 10% are estimated to be affected by endometriosis. Growth of tissue resembling the uterine mucosa outside the uterine cavity often causes severe menstrual pain, chronic pelvic pain and infertility for the …

About 1/3rd of Finish women in fertile age turn to family planning centers for advice on contraceptives whose regular monitoring is performed under guidelines issued by the Ministry of Health. A medical checkup 3 and 12 months after fitting…