Focal 68 Ga-FAPI-04 Uptake in Endometriosis at the Rectouterine Pouch

Zou Y, Yuheng Zou, Hu H, Haoyuan Hu, Hongbo Hu, Tian R, Rong Tian, Rang Wang
Clinical nuclear medicine · 2025 · vol. 50(12) , pp. e722–e723 · doi:10.1097/rlu.0000000000005846 · PMID:40096685 · W4408510244
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This case report describes a 25-year-old woman where 68Ga-FAPI-04 PET/CT incorrectly suggested peritoneal metastasis but was pathologically confirmed as endometriosis at the rectouterine pouch.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-15 · read from full text ⓘ

This case report describes a 25-year-old woman with newly diagnosed gastric cancer who underwent 68Ga-FAPI-04 PET/CT imaging that revealed focal uptake at the rectouterine pouch. Initial radiological interpretation suggested peritoneal metastasis from the gastric malignancy, but subsequent pathological examination confirmed the lesion was actually endometriosis. The findings highlight that endometriosis, characterized by chronic inflammation and fibrosis, can mimic malignant spread on this specific tracers scan. Relevance to endometriosis: This paper is centrally about endometriosis — specifically its appearance as focal tracer uptake in the rectouterine pouch mimicking metastatic disease.

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Abstract

Endometriosis is a benign condition characterized by chronic inflammation and fibrosis. We report the findings of endometriosis at the rectouterine pouch on 68 Ga-FAPI-04 PET/CT scan in a 25-year-old woman. The finding was initially thought as peritoneal metastasis from her newly diagnosed gastric cancer. However, subsequent pathologic examination confirmed that it was endometriosis.
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Endometriosis is a benign condition characterized by chronic inflammation and fibrosis. We report the findings of endometriosis at the rectouterine pouch on 68Ga-FAPI-04 PET/CT scan in a 25-year-old woman. The finding was initially thought as peritoneal metastasis from her newly diagnosed gastric cancer. However, subsequent pathologic examination confirmed that it was endometriosis. Focal 68Ga-FAPI-04 Uptake in Endometriosis at the Rectouterine Pouch Plain Language SummaryA 25-year-old woman with newly diagnosed gastric cancer underwent a 68Ga-FAPI-04 PET/CT scan, which initially suggested peritoneal metastasis at the rectouterine pouch. However, further pathological examination revealed the presence of endometriosis, a benign condition marked by chronic inflammation and fibrosis, rather than cancer spread. This case highlights the importance of accurate diagnosis in distinguishing endometriosis from malignant conditions, as both can appear similar on imaging scans. Understanding these differences is crucial for appropriate treatment planning and avoiding unnecessary interventions. Text is machine generated and may contain inaccuracies. FAQ

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

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