Peritoneal fluid 6-keto prostaglandin F1α levels in women with endometriosis

In: Diagnosis and Management of Tubo-Uterine Factors in Infertility · 1984 · pp. 87–93 · doi:10.1007/978-94-011-7621-7_18 · W4244142244
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This study investigated peritoneal fluid 6-keto prostaglandin F1α levels in women with endometriosis to better understand the association between endometriosis and infertility, particularly in cases without anatomical disorganization.

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This paper measured 6-keto prostaglandin F1α levels in peritoneal fluid from women with endometriosis to examine whether prostanoid changes might be associated with the reproductive and infertility-related effects of the disease. The study used peritoneal fluid sampling and high-level biochemical assessment of 6-keto PGF1α, but the provided text does not include details on sample size, matching, analytic methods, or effect magnitude. A key limitation stated in the available excerpt is conceptual: explanations for infertility associations are more straightforward when endometriosis is extensive and anatomically disorganized, whereas with lesser disease extent any such association would be harder to interpret. This paper is centrally about endometriosis — it focuses on peritoneal fluid 6-keto prostaglandin F1α levels in women with endometriosis.

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Abstract

There is considerable evidence to support an association between endometriosis and infertility’. When the endometriosis is extensive and there is anatomical disorganization of the pelvis, such an association would seem to be readily explained on the basis of impaired ovum pick-up. With lesser degrees of endometriosis such an association, if indeed one exists, is much more difficult to explain. Preview Unable to display preview. Download preview PDF. Similar content being viewed by others

References

Strathy, J.H., Molgaard, C.A., Coulam, C.B. and Melton, L. J. (1982). Endometriosis and infertility: a laparoscopic study of endometriosis among fertile and infertile women. Fertil. Steril., 38, 667 Schenken, R. S. and Asch, R. H. (1980). Surgical induction of endometriosis in the rabbit: effects on fertility and concentrations of peritoneal fluid prostaglandins. Fertil. Steril., 34, 581 Drake, T. S., O’Brien, W. F., Ramwell, P. W. and Metz, S. A. (1981). Peritoneal fluid thromboxane B, and 6-keto PGF,„ in endometriosis. Am. J. Obstet. Gynecol., 140, 401 Gal, D., Casey, M. L., Johnston, J. M. and MacDonald, P. C. (1982). Mesenchymeepithelial interactions in human endometrium. Prostaglandin synthesis in separated cell types. J. Clin. Invest., 70, 798 Peluso, J. J., Leiper, S. and Steger, R. W. (1980). Effects of PGF2, induced luteolysis and progesterone on follicular growth in pregnant mice. Prostaglandins, 19, 437 Wentz, A. C. and Jones, G. S. (1973). Transient luteolytic effect of prostaglandin Fa, in the human. Obstet. Gynaecol., 42, 172 Shaikh, A. (1972). Luteal regression in monkeys after the administration of estradiol and prostaglandin F2,,. Prostaglandins, 2, 227 Rock, J. A., Dubin, N. H., Ghodgaonkar, R. B., Bergquist, C. A., Erozan, Y.S. and Kimball, A. W. (1982). Cul-de-sac fluid in women with endometriosis: fluid volume and prostanoid concentration during the proliferative phase of the cycle - days 8 to 12. Fertil. Steril., 37, 747 Hall, J. C. (1982). Use of the t-test in the British Journal of Surgery. Br. J. Surg., 69, 55 Drake, T., O’Brien, W., Grunert, G. and Metz, S. (1980). Peritoneal fluid volumes in endometriosis. Fertil. Steril., 34, 280 Armstrong, D. (1981). Prostaglandins and follicular functions. J. Reprod. Fertil., 62, 283 Patwardhan, V.V. and Lanthier, A. (1980). Concentration of prostaglandins PGE and PGF, esterone, estradiol and progesterone in human corpora lutea. Prostaglandins, 20, 963 Coene, M.C., Van Hove, C., Claeys, M. and Herman, A.G. (1982). Arachidonic acid metabolism by cultured mesothelial cells. Biochim. Biophys. Acta, 710, 437 Green, K., Christensen, N. and Bygdeman, M. (1981). The chemistry and pharmacology of prostaglandins, with reference to human reproduction. J. Reprod. Fertil., 62, 269 Editor information Editors and Affiliations Rights and permissions Copyright information © 1984 MTP Press Limited About this chapter Cite this chapter Mudge, T.J., Jones, W.R., Walsh, J.A., James, M.J. (1984). Peritoneal fluid 6-keto prostaglandin F1α levels in women with endometriosis. In: Harrison, R.F., Bonnar, J., Thompson, W. (eds) Diagnosis and Management of Tubo-Uterine Factors in Infertility. Studies in Fertility and Sterility, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7621-7_18 Download citation DOI: https://doi.org/10.1007/978-94-011-7621-7_18 Publisher Name: Springer, Dordrecht Print ISBN: 978-94-011-7623-1 Online ISBN: 978-94-011-7621-7 eBook Packages: Springer Book Archive

Keywords

- Peritoneal Fluid - Pelvic Inflammatory Disease - Human Endometrium - Unexplained Infertility - Human Endometrial Stroma Cells4 These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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endometriosis

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References (13)

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