Ten Year Analysis Of Endometriosis Cases: Single Center Results

HARMANKAYA, ISMAIL
2024 · doi:10.5281/zenodo.12805621 · W6967864112
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This retrospective study analyzed 330 endometriosis cases from 2010-2020, finding the ovaries most frequently affected and associating masses with potential malignancy.

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This single-center retrospective study reviewed 330 pathology-confirmed endometriosis cases diagnosed between 2010 and 2020, extracted from a hospital information system, to characterize patients’ age, presenting complaints, endometriosis localization, associated benign or malignant lesions, and use of frozen examination. Patients ranged from 11 to 87 years (mean 45), most commonly presented with pelvic mass (79%) and abnormal uterine bleeding (19%), and the most frequently affected sites were the ovaries, including similar involvement of the right and left ovaries and bilateral ovarian involvement in 13.9% of cases. Frozen examination was performed in 26.3% of patients, and among those, 80% were diagnosed as benign and 20% as malignant, with the discussion noting links between endometriosis and endometrioid adenocarcinoma/clear cell carcinoma in ovarian cancer. The paper’s limitation is that it is based on a pathology case series from one center without a described control group, so generalizability to all endometriosis presentations is constrained. This paper is centrally about endometriosis — it analyzes localization, symptoms, and associated benign/malignant findings in a 10-year cohort of diagnosed endometriosis cases.

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Abstract

Aim: Endometriosis is a benign, chronic inflammatory diseasethat often involves the presence and enlargement of endometrialglands and stroma outside of the uterus. Endometriosis foci areoften seen in the abdominal cavity, in the ovaries, Phallopiantubes, ligament structures, on the outer surface of the uterusand the inner surface of the pelvis. The most common symptomsare chronic pelvic pain, dysmenorrhea, and infertility. In ourstudy, we aimed to determine the localization of endometriosis,accompanying symptoms and other accompanying lesions dueto the prevalence of endometriosis and its involvement in manydifferent regions.Material and Method: 330 cases diagnosed with endometriosisin the Department of Pathology between 2010 and 2020 werescanned through the hospital information system. The patientsdiagnosed with endometriosis were analyzed retrospectively interms of age, complaints, endometriosis location, accompanyingmalignant and benign lesions and frozen examination.Results: There were 330 patients diagnosed with endometriosis.The average age of the patients was 45 (SS 11,23), and it wasobserved that the latest patient was 11 years old and the oldestpatient was 87 years old. It was observed that the patients appliedto the gynecology and obstetrics clinic with complaints of pelvicmass (79%), abnormal uterine bleeding (19%) and pelvic pain(2%). It was observed that the most frequently affected area wasthe right (32,4%) and the left ovary (33%). In addition, bilateralovarian involvement was observed in 46(13,9%) patients andabdominal skin involvement in 29(8,8%) patients (Table 1). Frozenexamination was performed on 87(26,3%) patients and 70(80%)patients were diagnosed as benign and 17(20%) patients werediagnosed as malignant.Conclusion: Endometriosis is an important disease due to itswidespread prevalence in the society, significantly decreasing thequality of life of the person and causing a suspicion of malignancyby forming a mass. Although the pathogenesis of endometriosishas not been clearly explained, retrograde menstruation theoryis accepted today. It is a disease that can be easily treated withmedical or surgical treatments. It has been reported that especiallyendometrioid adenocarcinoma and clear cell carcinoma areassociated with endometriosis in patients with ovarian cancer.
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Material

and Method: 330 cases diagnosed with endometriosis in the Department of Pathology between 2010 and 2020 were scanned through the hospital information system. The patients diagnosed with endometriosis were analyzed retrospectively in terms of age, complaints, endometriosis location, accompanying malignant and benign lesions and frozen examination.

Results

There were 330 patients diagnosed with endometriosis. The average age of the patients was 45 (SS 11,23), and it was observed that the latest patient was 11 years old and the oldest patient was 87 years old. It was observed that the patients applied to the gynecology and obstetrics clinic with complaints of pelvic mass (79%), abnormal uterine bleeding (19%) and pelvic pain (2%). It was observed that the most frequently affected area was the right (32,4%) and the left ovary (33%). In addition, bilateral ovarian involvement was observed in 46(13,9%) patients and abdominal skin involvement in 29(8,8%) patients (Table 1). Frozen examination was performed on 87(26,3%) patients and 70(80%) patients were diagnosed as benign and 17(20%) patients were diagnosed as malignant.

Conclusion

Endometriosis is an important disease due to its widespread prevalence in the society, significantly decreasing the quality of life of the person and causing a suspicion of malignancy by forming a mass. Although the pathogenesis of endometriosis has not been clearly explained, retrograde menstruation theory is accepted today. It is a disease that can be easily treated with medical or surgical treatments. It has been reported that especially endometrioid adenocarcinoma and clear cell carcinoma are associated with endometriosis in patients with ovarian cancer. Files 4 237 Endometriozis.pdf Files (809.1 kB) | Name | Size | Download all | |---|---|---| | md5:68ea0ed956b53ba7399e878f286c7554 | 809.1 kB | Preview Download | Additional details Software - Repository URL - https://chronpmr.com/index.php/cpmr/article/view/237

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endometriosischronic_pelvic_paindysmenorrheainfertility

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