Comparison of the efficacy and safety of two advanced vessel sealing technologies in total laparoscopic hysterectomy

Burcu Aykan Yüksel, Burak Karadag, Burak Karadağ, Baris Mulayim, Barış Mülayim
Journal of Obstetrics and Gynaecology Research · 2019 · vol. 45(11) , pp. 2220–2227 · doi:10.1111/jog.14096 · PMID:31423703 · W2969974461
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This randomized trial found that LigaSure use in total laparoscopic hysterectomy significantly shortened operative time compared to Enseal, with no significant differences in total operative time, blood loss, or complications.

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Abstract

AIM: Adequately powered, randomized controlled studies evaluating efficacy and safety of advanced bipolar energy devices in gynecologic laparoscopic surgery are very few. We aimed to compare the two most commonly used devices in total laparoscopic hysterectomy. METHODS: This randomized controlled trial was carried out in the department of obstetrics and gynecology in an education and research hospital. One hundred thirty-two women who underwent total laparoscopic hysterectomy for benign indications were included. Women with age younger than 18 years, suspected malignancy, stage 3-4 endometriosis and cervical/intraligamentary leiomyoma were excluded. Patients were randomized preoperatively to LigaSure or Articulating Enseal. One experienced surgeon performed all operations. RESULTS: LigaSure was used in 67 patients and Enseal was used in 65 patients. Primary outcomes of the study were operative time (time from start of sealing and transection of the round ligament until completion of colpotomy) and total operative time (time from skin incision to skin closure). Secondary outcomes were intraoperative blood loss (blood lost during operative time period) and perioperative complications. Operative time was significantly shorter in LigaSure group (P = 0.001). Total operative time, intraoperative blood loss and perioperative complications were similar. When two groups were further classified according to uterine weight taking 300 g as cut-off value, operative time was significantly shorter in LigaSure group in both subgroups (P = 0.003 and P = 0.007). CONCLUSION: LigaSure use in total laparoscopic hysterectomy shortens operative time when compared with Enseal; without an apparent increase in intraoperative blood loss and perioperative complications. On the other side, total operative time remains unaffected.

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Condition tags

endometriosis

MeSH descriptors

Hysterectomy Laparoscopy Ligation Round Ligament of Uterus Adult Blood Loss, Surgical Blood Loss, Surgical Female Humans Hysterectomy Laparoscopy Ligation Middle Aged Operative Time Round Ligament of Uterus Treatment Outcome Uterus Uterus Uterus Young Adult

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