Clinical and hematological improvement in a patient receiving danazol therapy for myelofibrosis with myeloid metaplasia.
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Danazol therapy improved severe cytopenia, reduced myeloid metaplasia, and was well-tolerated in a patient with myelofibrosis and myeloid metaplasia.
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Abstract
We report the positive effect of danazol on clinical and hematological data in a patient with myelofibrosis and myeloid metaplasia. Severe cytopenia was corrected within 2 months and was maintained for an additional 2-month period. Myeloid metaplasia (lymph nodes and skin lesions) was greatly reduced. The patient experienced no side effects. We propose further trials to confirm the utility of this agent in this disease.
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Cited by (5)
- Danazol – możliwości wykorzystania w leczeniu chorób hematologicznych 2014
- Efficacy and tolerability of danazol as a treatment for the anaemia of myelofibrosis with myeloid metaplasia: long‐term results in 30 patients 2005
- Danazol treatment of idiopathic myelofibrosis with severe anemia. 2000
- Treatment of agnogenic myeloid metaplasia with danazol: A report of four cases 1996
- A review of 76 patients with myelodysplastic syndromes treated with danazol 1994
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- last seen: 2026-05-10T10:50:55.528521+00:00
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