The role of adjuvant therapy in Stage I ovarian cancer

M M Hreshchyshyn, R C Park, J A Blessing, H J Norris, D Levy, L D Lagasse, W T Creasman
American Journal of Obstetrics and Gynecology · 1980 · doi:10.1016/0002-9378(80)90024-1 · PMID:6252780
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Abstract

Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Ovarian Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma, Mucinous Adenocarcinoma, Mucinous Cystadenocarcinoma Cystadenocarcinoma Endometriosis Endometriosis Female Humans Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Staging Ovarian Neoplasms Ovarian Neoplasms

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Courtesy of the U.S. National Library of Medicine