Advances in Adenomyosis Diagnosis Utilizing Transvaginal Ultrasonography-A Short Summary

In: Open Access Journal of Reproductive System and Sexual Disorders · 2018 · vol. 2(1) · doi:10.32474/oajrsd.2018.02.000128 · W2922782694
article OA: diamond CC0 ⤵ 1 in-corpus citation
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AI-generated summary by claude@2026-06, 2026-06-07

Transvaginal ultrasonography can diagnose adenomyosis, a condition characterized by endometrial tissue within the myometrium causing uterine enlargement and cysts.

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AI-generated deep summary by claude@2026-06, 2026-06-07

This short communication discusses adenomyosis and the use of transvaginal ultrasonography (TVS) for its diagnosis, drawing on prior diagnostic-accuracy studies that compare 2D/3D TVS features with histopathology and report correlations with symptoms and infertility contexts. It highlights that TVS can show typical sonographic patterns reflecting adenomyosis, and cites Tellum et al. reporting a clinical prediction model with AUC 0.86 (95% CI 0.79–0.94), sensitivity 85%, and specificity 78%, using multiple ultrasound and symptom-related predictors. The paper explicitly notes limitations from earlier histology-based work, including selection bias toward older, more symptomatic patients, and notes that the proposed predictive model may not generalize because age, fertility status, association with deep infiltrating endometriosis, and adenomyosis subtype/extent were not incorporated. Relevance to endometriosis: it repeatedly contrasts symptom causation in adenomyosis versus endometriosis and notes that 48% of adenomyosis patients in the cited surgical cohort also had endometriosis, though the paper’s main focus is TVS-based diagnosis of adenomyosis.

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Abstract

Adenomyosis is a frequent condition, being present in 20% of general gynae population [1,2] and 30-40% of those attending assisted reproductive technology clinics, having a detrimental effect on cases of in vitro fertilization (IVF) [3,4]. Its main characteristics are presence of heterotopic endometrial glands and stroma within the myometrium, >2.5mm in depth of myometrium or more than one microscopic field at 10times magnification from the endometrium-myometrium junction, along with a variable degree of adjacent myometrial hyperplasia, causing globular and cystic enlargement of the myometrium, with some cysts filled with extravasated, hemolyzed red blood cells and siderophages [5].

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Condition tags

adenomyosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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