Endometrial Serous Carcinoma Arising from Adenomyosis: A Clinico-Pathological Insight

Amrita Talwar, Pushpanjali Behera, Arvind Ahuja, Bani Sarkar, Ravi Hari Phulware
Journal of family & reproductive health · 2021 · vol. 15(2) , pp. 125–129 · doi:10.18502/jfrh.v15i2.6454 · PMID:34721602 · W3166134105
article OA: diamond CC0 ⤵ 3 in-corpus citations
🔓 Open OA copy Full text JSON View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This case report describes a rare instance of serous endometrial carcinoma arising from adenomyosis in a post-menopausal woman, highlighting its infrequent occurrence and potentially poorer prognosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

This article presents a clinico-pathological insight into endometrial serous carcinoma reported as arising from adenomyosis, drawing on a case-based clinical and pathological description. The authors focus on characterizing the relationship between malignant endometrial serous histology and the adenomyotic tissue context through reported findings. A key limitation is that, as presented in a brief case report/insight format, the evidence level is restricted by lack of systematic sampling or broader comparative data. This paper is centrally about adenomyosis — it specifically describes endometrial serous carcinoma arising from adenomyosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Objective: Endometrial cancer (EC) is the most commonly diagnosed malignancy and has the secondhighest mortality rate among gynecological cancers. Adenomyosis is well-known for abnormal uterine bleeding and is a widely reported entity; however, an EC arising from the adenomyosis is a rare event; even rarer is the occurrence of serous endometrial carcinoma. Case report: A 60-year post-menopausal female presented with post-menopausal bleeding. Subsequently, she underwent a hysterectomy, which showed atrophic and cystic endometrium with extensive adenomyosis and atypical endometrial glands, which are diffusely P53 positive with intervening negative benign and focally positive dysplastic endometrial glands. A final diagnosis of serous endometrial carcinoma arising from adenomyosis was rendered. In a table format, previously reported serous endometrial carcinoma Arising cases from adenomyosis using PubMed search had been described. Conclusion: Serous endometrial carcinoma arising from adenomyosis (<20 cases reported) and has a slightly more dismal prognosis than those deriving from the endometrial cavity. Hence, this case report highlights the occurrence, rarity, and importance of such an entity.
Full text 1,809 characters · extracted from oa-html · click to expand
Publication Journal of Family & Reproductive Health Record type Journal article Published 16 June 2021 Authors Amrita Talwar | Pushpanjali Behera | Arvind Ahuja | Bani Sarkar | Ravi Hari Phulware The publisher of this work supports multiple resolution. The work is available from the following locations: {'doi': '10.18502/jfrh.v15i2.6454', 'member_id': '7770', 'member': 'Knowledge E DMCC', 'container-title': 'Journal of Family & Reproductive Health', 'primary-resource': 'http://publish.kne-publishing.com/index.php/JFRH/article/view/6454', 'tld': 'kne-publishing.com', 'clearbit-logo': '/static/no_logo.svg', 'coaccess': [], 'multiple-resolution': [{'url': 'https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1622', 'tld': 'tums.ac.ir', 'clearbit-logo': '/static/no_logo.svg'}, {'url': 'https://publish.kne-publishing.com/index.php/JFRH/article/view/6454', 'tld': 'kne-publishing.com', 'clearbit-logo': '/static/no_logo.svg'}], 'type': 'JOURNAL ARTICLE', 'published_date': '16 June 2021', 'publication': 'Journal of Family & Reproductive Health', 'title': 'Endometrial Serous Carcinoma Arising from Adenomyosis: A Clinico-Pathological Insight', 'name': None, 'id': None, 'location': None, 'display_doi': 'https://doi.org/10.18502/jfrh.v15i2.6454', 'grant_info': None, 'grant_info_funders': None, 'grant_info_funder_ids': '', 'grant_info_type': None, 'multiple_lead_investigators': [], 'multiple_co_lead_investigators': [], 'multiple_investigators': [], 'finances': [], 'project_description': None, 'award_amount': None, 'award_start': None, 'funding_scheme': None, 'internal_award_number': None, 'editors': None, 'authors': 'Amrita Talwar | Pushpanjali Behera | Arvind Ahuja | Bani Sarkar | Ravi Hari Phulware', 'chairs': None, 'supplementary_ids': None} https://doi.org/10.18502/jfrh.v15i2.6454 JSON XML

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-html ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

adenomyosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (15)

Cited by (3)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:24:14.728497+00:00
License: CC0 · commercial use OK