The standardization of traditional chinese medicine in refractory gastroesophageal reflux disease

Nan Wang, Wensheng Fan, Chenglei Gu, Luyang Zhao, Zhe Zhang
In: Chin J Gastroesophagol Reflux Dis(Electronic Edition) · 2016 · vol. 3(1) , pp. 12–15 · doi:10.3877/cma.j.issn.1674-6899.2016.01.005 · W3031942303
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This study retrospectively analyzed 31 postmenopausal women treated with laparoscopic surgery for ovarian endometriosis, finding radical surgery critical for diagnosis and treatment due to atypical presentation.

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This study evaluated the clinical efficacy of standardized traditional Chinese medicine prescriptions for 78 patients with refractory gastroesophageal reflux disease who had failed proton pump inhibitor therapy. Using a retrospective design based on six types of traditional Chinese medicine syndrome differentiation, researchers assessed symptom improvement alongside objective measures like high-resolution esophageal manometry and 24-hour pH monitoring over four weeks. The results indicated an overall effective symptom remission rate of 85.8%, with significant improvements in lower esophageal sphincter resting pressure and reflux frequency, although global acid exposure metrics such as the DeMeester score did not change significantly. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Objective To evaluate the effectiveness and safety of postmenopausal ovarian endometrial cyst. Methods From Jun. 2010 to Jun. 2015, there were 31 patients of postmenopausal ovarian endometriosis treated with laparoscopic surgery in our hospital. Clinical data were analyzed retrospectively. Results The average age was (55.39 ± 5.81) years old. The average period of menopause was (5.67 ± 5.32) years(95% CI 3.56-7.77).4 patients had the history of EMs, with 3 patients had received surgery. Chief complaint included 29 cases of pelvic mass, 6 cases of chronic pelvic pain, 1 case of postmenopausal vaginal bleeding. Endometriosis were preoperatively considered in 16 cases. All patients underwent radical surgery. Stages of r-AFS were 11 cases of stage Ⅰ and Ⅱ, 20 cases of stage Ⅲ and Ⅳ. The final pathologic findings of 31 cases were endometriosis with leiomyoma in 3 cases, adenomyosis in 5 cases, benign ovarian tumor in 4 cases and ovarian cancer in 3 cases. Conclusions Postmenopausal ovarian endometriosis was most likely the persistence of premenopausal endometriosis. Because its clinical picture was atypical, it was often misdiagnosed. The radical surgery was the critical methods for diagnosis and treatment. Key words: Postmenopause; Endometriosis; Diagnosis; Therapy
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Objective

To investigate the effects of traditional Chinese medicine in refractory gastroesophageal reflux disease patients who failed in the PPI Treatment.

Methods

78 refractory GERD patients were diagnosed by their clinical symptoms and the corresponding herb medicine was prescribed.The objective exams of esophagus pressure, PH monitor, the scale scores were measured to evaluate the effect.

Results

After 4 weeks treatment, effective rate of symptom remission was 85.8%(67/78). There were significant differences decrease in the pressure(P<0.05). The symptom scores improved after traditional Chinese medicine treatment.24-hour esophageal pH and DeMeester score before and after treatment indicate no significant difference.The resting pressure of the lower esophagus sphincter improved(P<0.05).

Conclusion

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