Chenglei Gu

ORCID: 0000-0002-9009-464X · 8 papers in corpus · active 2016-2021

Study types

  • article 5
  • other 2
  • meta-analysis 1

Condition tags

  • endometriosis 8
  • chronic_pelvic_pain 1
  • adenomyosis 1
other 2021
Exploring the Potential Key IncRNAs with Endometriosis by Construction of a ceRNA Network
International journal of general medicine ·doi:10.2147/IJGM.S321648

PURPOSE: The etiology and pathophysiology of endometriosis remain unclear. Current research indicates long noncoding RNA (lncRNA) may play an important role in the pathogenesis and development of endometriosis. However, the molecular mechan…

article 2020
Identification of MicroRNAs as Potential Biomarkers in Ovarian Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00148-z
other 2018
Effect of Mst1 on Endometriosis Apoptosis and Migration: Role of Drp1-Related Mitochondrial Fission and Parkin-Required Mitophagy
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology ·doi:10.1159/000487450

BACKGROUND/AIMS: Mitochondrial homeostasis is implicated in the development and progression of endometriosis through poorly defined mechanisms. Mst1 is the major growth suppressor related to cancer migration, apoptosis and proliferation. Ho…

article 2018
Integration analysis of microRNA and mRNA paired expression profiling identifies deregulated microRNA-transcription factor-gene regulatory networks in ovarian endometriosis
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-017-0319-5

BACKGROUND: The etiology and pathophysiology of endometriosis remain unclear. Accumulating evidence suggests that aberrant microRNA (miRNA) and transcription factor (TF) expression may be involved in the pathogenesis and development of endo…

article 2017
Identification of global transcriptome abnormalities and potential biomarkers in eutopic endometria of women with endometriosis: A preliminary study
Biomedical reports ·doi:10.3892/br.2017.902

The etiology and pathophysiology of endometriosis remain unclear. The aim of the current study was to identify a candidate pathogenic gene, as well as potential biomarkers of endometriosis using messenger RNA (mRNA) sequencing (mRNA-seq). T…

meta-analysis 2016
Association between oestrogen receptor alpha (ESR1) gene polymorphisms and endometriosis: a meta-analysis of 24 case-control studies
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2016.06.003

The PvuII (C > T), XbaI (A > G) and (TA)n polymorphisms of ESR1 gene are potentially associated with susceptibility to endometriosis. A meta-analysis was conducted to evaluate comprehensively the associations between endometriosis and ESR1 …

article 2016
Endometriosis research using capture microdissection techniques: Progress and future applications
Biomedical reports ·doi:10.3892/br.2016.758

Endometriosis is a common gynecological disease with high prevalence, while its etiology and pathophysiology have remained to be fully elucidated. Previous evidence suggested that this disorder may be in part or completely of somatic origin…

article 2016
The standardization of traditional chinese medicine in refractory gastroesophageal reflux disease
·doi:10.3877/cma.j.issn.1674-6899.2016.01.005

Objective To evaluate the effectiveness and safety of postmenopausal ovarian endometrial cyst. Methods From Jun. 2010 to Jun. 2015, there were 31 patients of postmenopausal ovarian endometriosis treated with laparoscopic surgery in o…