Changes and Factors Influencing Health-related Quality of Life After Hysterectomy in Premenopausal Women with Benign Gynecologic Conditions

Ya‐Ling Yang, Yueh‐Chih Chen, Yu-Mei Yu Chao, Grace Yao
In: Journal of the Formosan Medical Association · 2006 · vol. 105(9) , pp. 731–742 · doi:10.1016/s0929-6646(09)60201-1 · PMID:16959621 · W2138846271
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This prospective study investigated health-related quality of life before and after hysterectomy in premenopausal women, finding improved physical function and self-rated health, with employment, education, and blood transfusion predicting mental health outcomes.

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This prospective follow-up study of 38 premenopausal women undergoing abdominal hysterectomy for nonmalignant causes assessed health-related quality of life before and after surgery using SF-36 and self-rated health status, analyzed with methods for repeatedly measured outcomes. All participants showed significant improvement in the SF-36 physical component summary and in self-rated health status across repeated assessments, while the mental component summary showed no significant change. Hemoglobin level before surgery predicted HRQoL preoperatively, and factors including employment, more education, and previous blood transfusion were associated with higher post-surgery MCS scores. The study’s limitation is that it focuses on women receiving abdominal hysterectomy for benign gynecologic conditions, which may not generalize beyond this specific setting. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Journal of the Formosan Medical Association (Jan 2006) Changes and Factors Influencing Health-related Quality of Life After Hysterectomy in Premenopausal Women with Benign Gynecologic Conditions Abstract A hysterectomy affects a woman's health. This study was performed to identify the factors that affect health-related quality of life (HRQoL) before and after hysterectomy in premenopausal women. Methods: This prospective follow-up study recruited 38 women (age range, 33-52 years) who underwent abdominal hysterectomy for nonmalignant causes. SF-36 and self-rated health status were used to assess HRQoL before and after hysterectomy. Data were analyzed using descriptive statistics, nonparametric tests and the generalized estimating equation method for modeling the repeatedly measured responses. Results: Patients' attitudes toward hysterectomy and subsequent sexual activity were influenced by the surgery. All patients showed significant improvements in the physical component summary (PCS) of SF-36 (mean, 42.1-51.0), but there was no significant difference in the mental component summary (MCS). The significant improvements were found from the five repeated measurements of the self-rated health status (mean, 6.0-7.3). Hemoglobin level was the most important predictor of HRQoL before surgery. Women in employment, with more years of education and previous blood transfusion had high MCS scores after surgery. Conclusion: The overall self-rated health status and PCS showed significant improvements after hysterectomy. Having had a blood transfusion, being educated and employed were positively associated with MCS score after surgery. These findings are vital for preoperative counseling for women undergoing hysterectomy. Keywords

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