Az endometriosis hatása az életminőségre Magyarországon | The impact of endometriosis on quality of life in Hungary

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This Hungarian study found a 3.9-year diagnostic delay for endometriosis, with significant quality of life impairment and pain reduction after treatment, regardless of surgical or combined therapy type.

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Abstract

Bevezetes: Az endometriosis az egyik leggyakoribb nőgyogyaszati betegseg, tobb mint 70 millio felnőtt es serdulő nőt erint vilagszerte. Celkitűzes: A szerzők az endometriosis diagnosztikus kesedelmi idejenek meghatarozasat, a sebeszi, illetve kombinalt műteti kezeles hatekonysaganak vizsgalatat, valamint a betegek eletminősegenek felmereset tűztek ki celul. Modszer: A bevalogatasi kriteriumoknak megfelelő 240, endometriosisban szenvedő nőből 84 vett reszt a retrospektiv es prospektiv kerdőives felmeresben. Eredmenyek: A tunetek kezdetetől a diagnozisig atlagosan 3,9 ev telt el. A tunetek fellepesekor a betegek 89%-a, a kezelest kovető prospektiven vizsgalt honapokban 28%-a panaszkodott fajdalomrol (p = 0,025). A sebeszi kezeles es a műteti terapiaval kombinalt konzervativ kezeles hatekonysaga kozott nem talaltak szignifikans kulonbseget (p = 0,85). A munkahelyi teljesitmeny csokkeneseről a betegek 47%-a, mig a szemelyes kapcsolatok kedvezőtlen alakulasarol a vizsgalatban reszt vevők 40%-a szamolt be. Az eletminősegre standardizalt eletevveszteseg egy ev alatt 0,147 volt. Kovetkeztetesek: Jelen felmeres az első hazai prospektiv, az endometriosis eletminősegre gyakorolt hatasat vizsgalo tanulmany. A betegsegre hosszu diagnosztikus keses jellemző. Az endometriosis jelentősen rontja az eletminőseget, de adekvat kezelessel a panaszok csokkenthetők. Orv. Hetil., 2013, 154, 1426–1434. | Introduction: Endometriosis is one of the most common gynaecological diseases affecting 70 million women worldwide. Aim: The aims of this study were to determinate the diagnostic delay of endometriosis, to assess the effectiveness of surgical and combined therapy and to analyse the quality of life of women suffering from this disease. Method: Of the 240 patients with endometriosis enrolled in the study, 84 patients filled in a prospective as well as a retrospective questionnaire. Results: There was a 3.9 year delay from the onset of symptoms to the definitive diagnosis. Before therapy, 89% of the patients reported endometriosis related pain, while after therapy only 28% in the prospectively investigated months (p = 0.025). There was no significant difference between the outcome of surgical treatment alone and combined operative and medical therapy (p = 0.85). Reduced productivity at work was present in 47% of the patients and 40% of the patients reported impaired personal relationship, too. Endometriosis-associated symptoms generated 0.147 quality-adjusted life years per woman. Conclusions: This study is the first ever prospective survey to investigate the impact of endometriosis on the quality of life in Hungary. The results indicated a long diagnostic delay. Both surgical and combined therapies proved to be efficient. Endometriosis impaired health-related quality of life, but adequate therapy attenuated the severity of symptoms. Orv. Hetil., 2013, 154, 1426–1434.

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