In vivo study of endometriosis in mice by photoacoustic microscopy
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⤵ 3 in-corpus citations
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Photoacoustic microscopy was used to noninvasively image implanted endometriosis tissue in vivo in mice, demonstrating high contrast, 3D imaging capabilities, and diagnostic sensitivity and specificity.
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Abstract
Endometriosis (EM) impacts the healthcare and the quality of life for women of reproductive age. However, there is no reliable noninvasive diagnosis method for either animal study or clinical use. In this work, a novel imaging method, photoacoustic microscopy (PAM) was employed to study the EM on the mouse model. Our results demonstrated the PAM noninvasively provided the high contrast and 3D imaging of subcutaneously implanted EM tissue in the nude mouse in vivo. The statistical study also indicated PAM had high sensitivity and specificity in the diagnosis of EM in this animal study. In addition, we also discussed the potential clinical application for PAM in the diagnosis of EM.
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Cites (4)
- Endometriosis 2010
- EPIDEMIOLOGY OF ENDOMETRIOSIS 1997
- Diagnostic accuracy of laparoscopy, magnetic resonance imaging, and histopathologic examination for the detection of endometriosis 2003
- Transplantation of normal and ectopic human endometrial tissue into athymic nude mice 1984
Cited by (3)
- Photoacoustic Imaging Endometriosis Lesions with Nanoparticulate Polydopamine as a Contrast Agent 2023
- Emerging bioengineering breakthroughs in precision diagnosis and therapy for endometriosis and adenomyosis 2024
- Burrowing behavior is a potential non-invasive proxy for lesion development in a syngeneic murine model of endometriosis 2025
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Cited by (3)
- Burrowing behavior is a potential non-invasive proxy for lesion development in a syngeneic murine model of endometriosis 2025
- Emerging bioengineering breakthroughs in precision diagnosis and therapy for endometriosis and adenomyosis 2024
- Photoacoustic Imaging Endometriosis Lesions with Nanoparticulate Polydopamine as a Contrast Agent 2023
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- europepmc
- last seen: 2026-06-23T06:15:44.889181+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:18:35.150238+00:00
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