Intrauterine insemination: is the timing correct?
Observational
OA: closed
AI-generated summary
This retrospective cohort study of 578 intrauterine insemination cycles found that clinical pregnancy rates were significantly higher when the procedure was performed after observing follicle rupture via transvaginal ultrasonography compared to when it was not evident.
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Abstract
OBJECTIVE: To evaluate the impact of follicle rupture on pregnancy rate in intrauterine insemination.
MATERIAL AND METHOD: Retrospective cohort study. Evidence of follicle rupture was assessed by transvaginal ultrasonography following IUI. Two hundred ninety-six couples with unexplained infertility and 121 couples with male factor subfertility were included. Results of 578 cycles were analyzed here.
RESULT: Clinical pregnancy rate was 23.5% (64/272) in the group when follicle rupture was evident by transvaginal ultrasonography, while it was only 8.8% (27/306) when follicle rupture was not evident (p < 0.001).
CONCLUSION: Postponing IUI until observation of follicle rupture may yield a higher pregnancy rate.
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- europepmc
- last seen: 2026-10-11T09:27:45.537177+00:00
- pubmed
- last seen: 2026-10-08T21:05:43.569505+00:00
- unpaywall
- last seen: 2026-10-12T06:33:14.382917+00:00