Dysfunctional Uterine Bleeding During Adolescence

Dysfunctional uttering bleeding (DUB) is an abnormal uterine bleeding in the absence of organic cause. It is usually a painless, excessive and irregular endometrial bleeding that may be prolonged, and it is not attributable to any underlying structural or systemic disease. The etiology DUB arises out of continuing maturation of the hypothalamus, such that the eventual establishment of normal pulsatile gonadotropin release leads to normal menstrual cycle control. DUB is usually seen during adolescence. In about 95% of cases DUB is due to the late maturation of the hypothalamic–pituitary–ovarian axis. The evaluation of DUB cases includes a detailed family and personal history as well as a careful gynecological examination, including visualization of the cervix, even in virgin young girls (vaginoscopy), laboratory studies: hematocrit, hemospherin, and others, pelvic ultrasonography, radiological imaging procedures, and rarely hysteroscopy or/and curretage. Endocrinological tests are not always necessary. The disease is classified as mild, moderate, or severe. In mild DUB cases the use of combined oral contraceptives is occasionally indicated as well as a careful follow-up. In cases of moderate degree the use of the new generation 17β-estradiol or the cyclic use of progestagenic compounds is the treatment of choice. Cyclic oral progestogens are administered for the same 10 days every month to prevent the action of unopposed estrogens and stabilize the endometrium. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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- Luteinizing Hormone - Immune Thrombocytopenic Purpura - Endometrial Thickness - Premature Ovarian Failure - Endometrial Hyperplasia These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.