Chronic pelvic pain and endometriosis in adolescents

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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-27 ⓘ

This review details chronic pelvic pain and endometriosis in adolescents, discussing current evaluation and treatment approaches while highlighting recent research on pathogenesis and the need for adolescent-specific therapies.

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This review examines the evaluation and treatment of chronic pelvic pain and endometriosis in adolescents, noting that while disease rates are known, the underlying pathogenesis remains unclear. The authors highlight a significant gap in clinical application, as most innovative strategies are derived from adult algorithms rather than adolescent-specific data. Consequently, the paper calls for future research to identify progressive cases early and develop less invasive therapies that target inflammatory pathways to reduce morbidity. This paper is centrally about endometriosis — specifically its presentation and management challenges within the adolescent population.

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Abstract

PURPOSE OF REVIEW: This review will provide a detailed account of chronic pelvic pain and endometriosis, two conditions that frequently occur in adolescents. Current approaches used to evaluate and treat these patients will be addressed. RECENT FINDINGS: Although previous investigations have established relative rates of disease and basic treatment algorithms for endometriosis in adolescents, its pathogenesis is yet to be explained. Recent scientific works have focused on the interplay of specific genes and the role of host immune response. Despite such progress, we have not yet learned how to apply this knowledge to clinical use. Most innovative treatment strategies are based on algorithms generated primarily for adults, with only a small percentage focusing on adolescents. SUMMARY: Treating pain associated with endometriosis may be facilitated by early intervention. Future study should focus on identifying adolescents with progressive disease and introducing less invasive therapies that could reverse inflammatory pathways and minimize subsequent morbidity.
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Chronic pelvic pain and endometriosis in adolescents - Meir Jonathon Solnik Purpose of review This review will provide a detailed account of chronic pelvic pain and endometriosis, two conditions that frequently occur in adolescents. Current approaches used to evaluate and treat these patients will be addressed. Recent findings Although previous investigations have established relative rates of disease and basic treatment algorithms for endometriosis in adolescents, its pathogenesis is yet to be explained. Recent scientific works have focused on the interplay of specific genes and the role of host immune response. Despite such progress, we have not yet learned how to apply this knowledge to clinical use. Most innovative treatment strategies are based on algorithms generated primarily for adults, with only a small percentage focusing on adolescents. Summary Treating pain associated with endometriosis may be facilitated by early intervention. Future study should focus on identifying adolescents with progressive disease and introducing less invasive therapies that could reverse inflammatory pathways and minimize subsequent morbidity.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Pelvic Pain Adolescent Adolescent Chronic Disease Chronic Disease Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Female Female Humans Humans Patient Selection Patient Selection Pelvic Pain Pelvic Pain Pelvic Pain

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europepmc
last seen: 2026-10-16T06:09:50.462052+00:00
pubmed
last seen: 2026-10-08T21:03:58.311020+00:00
unpaywall
last seen: 2026-10-16T06:24:35.758740+00:00
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