ENDOMETRIOSE: REVISÃO SISTEMÁTICA SOBRE A FISIOPATOLOGIA, COMPLICAÇÕES E ABORDAGENS TERAPÊUTICAS PARA UMA DOENÇA CRÔNICA COMPLEXA
This systematic review identified chronic pelvic pain, infertility, and inflammation as key complications of endometriosis, commonly treated with hormonal or surgical approaches, with new therapies under investigation.
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This paper is a systematic review that analyzed scientific publications on endometriosis to identify key complications and treatment approaches. Searches in PubMed using combinations of terms (e.g., infertility and endometriosis/endometrial diseases) yielded 23 articles that were selected for detailed analysis, and the review reports major complications including chronic pelvic pain, infertility, and inflammation-related problems from endometriotic tissue outside the uterus. Treatments most commonly discussed are hormonal therapies such as progestins and GnRH agonists, with mention of other investigated options including aromatase inhibitors and selective hormone receptor modulators, while surgical approaches are described as often needed for severe or treatment-resistant cases; a stated limitation is that the included evidence is derived from a single database search strategy with a specific keyword set. This paper is centrally about endometriosis — it reviews its pathophysiology, complications, and therapeutic approaches.
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References (13)
- A Lifelong Impact on Endometriosis: Pathophysiology and Pharmacological Treatment via openalex
- An Estrogen-NK Cells Regulatory Axis in Endometriosis, Related Infertility, and Miscarriage via openalex
- Ectopic Endometrium: The Pathologist’s Perspective via openalex
- Endometriosis-Associated Macrophages: Origin, Phenotype, and Function via openalex
- MicroRNAs Dysregulation as Potential Biomarkers for Early Diagnosis of Endometriosis via openalex
- New Therapeutics in Endometriosis: A Review of Hormonal, Non-Hormonal, and Non-Coding RNA Treatments via openalex
- Pathogenesis of Endometriosis: The Origin of Pain and Subfertility via openalex
- Phytoestrogens for the Management of Endometriosis: Findings and Issues via openalex
- Role of the gut microbiota in the pathogenesis of endometriosis: a review via openalex
- The Molecular Link between Obesity and the Endometrial Environment: A Starting Point for Female Infertility via openalex
- W4328135802 via openalex
- W4281755119 via openalex
- W3194419458 via openalex
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- last seen: 2026-06-10T17:14:06.276822+00:00