An Unusual Case of Recurrence of Thoracic Endometriosis in a Patient Post-oophorectomy

In: The Journal of Obstetrics and Gynecology of India · 2025 · doi:10.1007/s13224-025-02269-4 · W7117451433
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This case report describes recurrent thoracic endometriosis in a patient after oophorectomy and hysterectomy that did not respond to medical management.

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This case report describes a 39-year-old woman with recurrent thoracic endometriosis who developed right-sided shoulder pain after prior episodes of catamenial pneumothorax treated with right pleurectomy in 2018, followed by total laparoscopic hysterectomy with bilateral salpingo-oophorectomy in 2020 for deep infiltrating endometriosis. Despite postoperative cyclic combined hormonal pills for two years, she experienced recurrent symptoms about a year after starting hormonal contraception and underwent redo thoracotomy with excision of a deep infiltrating endometriotic nodule. The authors note that the role of preoperative hormone therapy is questionable and emphasize that definitive multidisciplinary surgical management and continuous postoperative hormonal therapy (oral contraceptives or GnRH analogues) were associated with reduced recurrence of symptoms in their case. This paper is centrally about endometriosis — specifically thoracic endometriosis with recurrence after oophorectomy and surgical/hormonal management.

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Abstract

Background Thoracic Endometriosis (TES) is a condition which is characterised by the presence of endometrial tissue in airways, pleura and lung parenchyma. It is a rare pathology which typically presents as catamenial pneumothorax, haemothorax, haemoptysis and pulmonary nodules. Our case report addresses the challenges in diagnosing and treating TES, particularly in cases with recurrent pleural lesions. In our case report, we present a case of recurrent TES post-oophorectomy which did not respond to medical management. Case Description A 39-year-old woman, known case of recurrent thoracic endometriosis, presented with right-sided shoulder pain for a duration of 1 year. She gave a history of recurrent catamenial pneumothorax for which the patient underwent right-sided pleurectomy in 2018. In view of severe dysmenorrhea, patient was evaluated and diagnosed with bilateral pelvic ovarian cysts with deep infiltrating endometriosis and underwent total laparoscopic hysterectomy with bilateral salpingo-oophorectomy in 2020. Postoperatively, she was started on cyclic combined hormonal pills which she continued for a duration of 2 years. One year after initiation of the hormonal contraceptive, the patient developed complaints of right-sided shoulder pain, following which she was taken up for redo thoracotomy with excision of deep infiltrating endometriotic nodule.

Conclusion

The role of preoperative hormone therapy is questionable, whereas definitive surgical management using a multidisciplinary approach offer better symptom relief and lower recurrence rates. Following surgical excision of lesions, hormone therapy in the form of oral contraceptive pills and GnRH analogues when used continuously are found to have a definitive reduction in recurrence of symptoms. Similar content being viewed by others

References

Zondervan KT, Becker CM, Missmer SA. Endometriosis. Longo DL, editor. N Engl J Med [Internet]. 2020 Mar 26 [cited 2025 Jan 29];382(13):1244–56. Available from: https://pubmed.ncbi.nlm.nih.gov/32212520/ Yen CF, Kim MR, Lee CL. Epidemiologic factors associated with endometriosis in East Asia. Gynecol Minim Invasive Ther. 2019;8(1):4–11. Hirata T, Koga K, Osuga Y. Extra-pelvic endometriosis: a review. Reprod Med Biol. 2020;19(4):323–33. Saadeh R, Finianos E, El Hajj H, IMR Press Limited. Urinary tract endometriosis: a review of literature. Clin Exp Obstet Gynecol. 2024. https://doi.org/10.31083/j.ceog5108172. Zorbas KA, Economopoulos KP, Vlahos NF. Continuous versus cyclic oral contraceptives for the treatment of endometriosis: a systematic review. Arch Gynecol Obstet. 2015;292(1):37–43. Author information Authors and Affiliations Corresponding author Ethics declarations Conflict of interest The authors declare that there is no conflict of interest Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Supplementary Information Below is the link to the electronic supplementary material. Rights and permissions Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. About this article Cite this article Farhan, S., Yusuf, N. & Rahman, H. An Unusual Case of Recurrence of Thoracic Endometriosis in a Patient Post-oophorectomy. J Obstet Gynecol India (2025). https://doi.org/10.1007/s13224-025-02269-4 Received: Accepted: Published: Version of record: DOI: https://doi.org/10.1007/s13224-025-02269-4

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