ANGKA KEJADIAN KEHAMILAN SETELAH LAPAROSKOPI OPERATIF PADA INFERTILITAS AKIBAT ENDOMETRIOSIS

In: Jurnal Ilmu Kedokteran dan Kesehatan · 2022 · vol. 9(3) · doi:10.33024/jikk.v9i3.6698 · W4317732171
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This study found a 23.4% pregnancy rate after operative laparoscopy for endometriosis-related infertility, with longer infertility duration significantly impacting outcomes.

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The paper studied the incidence of pregnancy after operative laparoscopy in infertile patients with endometriosis, using a review/summary framework based on the provided article context and related references rather than reporting original trial-level methods or effect estimates. The key reported outcome is the “angka kejadian kehamilan” (incidence of pregnancy) following laparoscopic surgery for endometriosis-associated infertility. A major caveat explicitly reflected in the available text is that the submission does not provide detailed methodology, population characteristics, or analytic details within the excerpt, limiting assessment of validity and generalizability. This paper is centrally about endometriosis — it specifically addresses pregnancy incidence after operative laparoscopy in infertility caused by endometriosis.

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Abstract

Probabilitas kehamilan pada wanita infertil yang menderita endometriosis adalah sekitar dua kali lebih rendah daripada wanita dengan infertilitas idiopatik. Farmakoterapi untuk endometriosis tidak cukup efektif meningkatkan fertilitas, namun pembedahan dapat meningkatkan kesuburan. Penelitian ini bertujuan untuk mengetahui angka kejadian kehamilan setelah laparoskopi operatif pada infertilitas akibat endometriosis serta faktor yang mempengaruhinya. Penelitian dalam bentuk survival analysis dilakukan sejak bulan Januari sampai Juni 2017. Pada hasil penelitian, angka kejadian kehamilan adalah 23,4. Usia ≥30,5 tahun 6,061 kali lebih berisiko tidak bisa hamil setelah laparoskopi operatif dibandingkan usia 2,5 tahun secara signifikan lebih berisiko 18,6 kali tidak bisa hamil setelah laparoskopi operatif dibandingkan ≤ 2,5 tahun (p6 (p= 0,002). Uji multivariat didapatkan durasi infertilitas berpengaruh secara signifikan terhadap kejadian kehamilan setelah laparoskopi operatif pada pasien infertilitas akibat endometriosis (p= 0,028). Durasi infertilitas merupakan faktor risiko yang paling mempengaruhi angka kejadian kehamilan.
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ANGKA KEJADIAN KEHAMILAN SETELAH LAPAROSKOPI OPERATIF PADA INFERTILITAS AKIBAT ENDOMETRIOSIS Sari Kata Kunci Teks Lengkap: PDFReferensi Adamson GD, Pasta DJ. 2010. Endometriosis Fertility Index: the new, validated endometriosis staging system. Fertil Steril. 94(5):1609-15. Allaire C. 2006. Endometriosis and infertility: a review. J Reprod Med. 51(3):164-8. Allow AK, Abdulmogny SS, Maryam B, Al-Ani KNG, Fakhrildin MB, Muhamad W. 2016. The relationship between duration of infertility and intrauterine insemination: a multi-centers study. J Clin Dev Biol. 3(13):1-7. Berlanda N, Varcellini P, Somigliana E, Frattaruolo MP, Buggio L, Gattei U. 2013. Role of surgery in endometriosis-associated subfertility. Semin Reprod Med. 31(2013):133-43. Bulletti C, Coccia ME, Battistoni S, Borini A. 2010. Endometriosis and infertility. J Assist Reprod Genet. 27(2010):441-7. George K, Kamath MS. 2010. Fertility and age. J Hum Reprod Sci. 3(3):121-3. Hoffman BL, Schorge JO, Schaffer JI, Halvorson LM, Bradshaw KD, Cunningham FG. 2012. Endometriosis In: Carr BR, eds. Williams Gynecology, 2nd ed. New York: The Mcgraw-Hill Companies. Hou Z, Mao YD, Liu JY. 2013. Study on the factors associated with clinical pregnancy rate of in-vitro fertilization in endometriosis related infertility. Zhonghua Fu Chan Ke Za Zi. 48(1):6-10. Jin X, Beguerie JR. 2014. Laparoscopic surgery for subfertility related to endometriosis: A meta-analysis. Taiwan J Obstet Gynecol. 53(3):303-8. Lee HJ, Lee JE, Ku SY, Kim SH, Kim JG, Moon SY. 2013. Natural conception rate laparoscopy surgery in infertile women with endometriosis. Clin Exp Reprod Med. 40(1):29-32. Li X, Zeng C, Zhou YF, Yang HX, Shang J, Zhu, SN. 2017. Endometriosis fertility index for predicting pregnancy after endometriosis surgery. Chin Med J. 130(16):1932-7. Parazzini F. 1999. Ablation of lesions or no treatment in minimal-mild endometriosis in infertil women: a randomized trial. Hum Reprod. 14 (1999):1332-4. Slabuszewska-Jozwiak A, Ciebiera M, Baran A, Jakiel G. 2015. Effectiveness of laparoscopic surgeries in treating infertility related to endometriosis. Ann Agric Environ Med. 22(2):329-31. Swift BE, Liu KE. 2014. The effect of age, ethnicity, and level of education on fertility awareness and duration of infertility. J Obstet Gynaecol Can. 36(11):990-6. Vercellini P, Fedele L, Aimi G, Giorgi OD, Consonni D, Crosignani PG. 2006. Reproductive performance, pain recurrence and disease relapse after conservative surgical treatment for endometriosis: the predictive value of the current classification system. Hum Reprod. 21(10):2679-85. Wang W, Li R, Fang T, Huang L, Ouyang N, Wang L, et al. 2013. Endometriosis fertility index score maybe more accurate for predicting the outcomes of in vitro fertilization than r-AFS classification in women with endometriosis. Reprod Biol Endocrinol. 11(2013):112. DOI: https://doi.org/10.33024/jikk.v9i3.6698 Refbacks - Saat ini tidak ada refbacks. ##submission.copyrightStatement## ##submission.license.cc.by-nc4.footer## Pendidikan Dokter Universitas Malahayati Lampung This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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