Extrauterine Endometrial Stromal Sarcoma: A Case Report

Smera Saikumar, Lakshmi Haridas Kamala, Saxena Renu
In: Indian Journal of Gynecologic Oncology · 2023 · vol. 21(2) · doi:10.1007/s40944-023-00721-9 · W4376619096
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This case report describes a young woman with inoperable low-grade extrauterine endometrial stromal sarcoma involving bilateral ovaries, omentum, and peritoneum, treated with endocrine therapy and surgery.

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This paper reports a case of extrauterine endometrial stromal sarcoma, describing a young patient with low-grade disease that was inoperable at presentation and involved bilateral ovaries, the omentum, peritoneum, and hemorrhagic third-space collections, while the uterus appeared radiologically normal. The authors note a major predisposing factor is endometriosis and document initial management with palliative endocrine therapy followed by complete cytoreductive surgery, with ongoing treatment using an aromatase inhibitor. The main limitation is that the study is a single case report, so findings are not generalizable beyond this patient. This paper is centrally about endometriosis — it specifically frames endometriosis as the basic predisposing factor for extrauterine endometrial stromal sarcoma and presents an extrauterine stromal sarcoma case with gynecologic involvement.

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Abstract

Extrauterine endometrial stromal sarcomas are rare malignancies, with 181 cases reported so far. The basic predisposing factor is endometriosis, and ovary is the most common extrauterine site. Low-grade varieties are the most common subtypes encountered. Our patient is a young lady with low-grade extrauterine endometrial stromal sarcoma inoperable disease at presentation involving bilateral ovaries, omentum, peritoneum and hemorrhagic third space collections. The uterus was radiologically normal. She initially received palliative endocrine therapy and later underwent complete cytoreductive surgery. Currently, she is on an aromatase inhibitor. Similar content being viewed by others

References

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