{"paper_id":"6bd47d38-97a1-4103-aab8-9f325f0eb9ab","body_text":"Abstract\nExtrauterine endometrial stromal sarcomas are rare malignancies, with 181 cases reported so far. The basic predisposing factor is endometriosis, and ovary is the most common extrauterine site. Low-grade varieties are the most common subtypes encountered. Our patient is a young lady with low-grade extrauterine endometrial stromal sarcoma inoperable disease at presentation involving bilateral ovaries, omentum, peritoneum and hemorrhagic third space collections. The uterus was radiologically normal. She initially received palliative endocrine therapy and later underwent complete cytoreductive surgery. Currently, she is on an aromatase inhibitor.\nSimilar content being viewed by others\nReferences\nNovetsky AP, Powell MA. Management of sarcomas of the uterus. Curr Opin Oncol. 2013;25(5):546–52.\nEfared B, Sidibé IS, Erregad F, Hammas N, Chbani L, El Fatemi H. Extra-uterine low grade endometrioid stromal sarcoma arising from ovarian endometriosis: a case report and review of the literature. Gynecol Oncol Res Pract. 2019;6:2.\nHuang HY, Ladanyi M, Soslow RA. Molecular detection of JAZF1-JJAZ1 gene fusion in endometrial stromal neoplasms with classic and variant histology: evidence for genetic heterogeneity. Am J Surg Pathol. 2004;28(2):224–32.\nLee CH, Mariño-Enriquez A, Ou W, Zhu M, Ali RH, Chiang S, et al. The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor. Am J Surg Pathol. 2012;36(5):641–53.\nMasand R, Euscher E, Deavers M, Malpica A. Extrauterine endometrial stromal sarcoma: a pathologic study of 63 cases with clinical correlation. Am J Surg Pathol. 2013;37:1635–47.\nClair K, Wolford J, Veran-Taguibao S, Kim G, Eskander RN. Primary low-grade endometrial stromal sarcoma of the omentum. Gynecol Oncol Rep. 2017;21:119–21.\nLiu Z, Ding J, Li X, Yu K. Endometrial stromal sarcoma arising in vagina. Int J Clin Exp Pathol. 2013;6:2997–3002.\nAyuso A, Fadare O, Khabele D 2013 A Case of Extrauterine Endometrial Stromal Sarcoma in the Colon Diagnosed Three Decades after Hysterectomy for Benign Disease. Hindawi Publishing Corporation. Case Reports in Obstetrics and Gynecology. 2013, Article ID 202458, 3 pages\nDeb PQ, Heller DS. Extrauterine endometrial stromal sarcoma: a systematic review and outcome analysis. Ann Diagn Pathol. 2022;59: 151966.\nFunding\nThere are no sources of funding for this work.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nEthics declarations\nConflict of interest\nThere are no competing interests among the authors.\nAdditional information\nPublisher's Note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nRights and permissions\nSpringer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.\nAbout this article\nCite this article\nSaikumar, S., Haridas, L. & Renu, S. Extrauterine Endometrial Stromal Sarcoma: A Case Report. Indian J Gynecol Oncolog 21, 44 (2023). https://doi.org/10.1007/s40944-023-00721-9\nReceived:\nRevised:\nAccepted:\nPublished:\nVersion of record:\nDOI: https://doi.org/10.1007/s40944-023-00721-9","source_license":"CC0","license_restricted":false}