The utility of ultrasound elastography in differentiation of endometriomas and hemorrhagic ovarian cysts

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Acoustic radiation force impulse imaging demonstrated endometriomas have significantly higher stiffness than hemorrhagic ovarian cysts, with a cutoff value of 3.81 m/s yielding high sensitivity and specificity for differentiation.

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This study evaluated acoustic radiation force impulse (ARFI) ultrasound elastography for differentiating endometriomas from hemorrhagic ovarian cysts in 70 consecutive women with 84 ovarian cysts showing high internal echogenicity. After excluding simple cysts and hemorrhagic cysts with septations or mural nodules with detectable Doppler flow, the authors measured cyst shear wave velocity (SWV) and compared elastographic stiffness between confirmed endometriomas (n=42) and hemorrhagic ovarian cysts (n=36). Endometriomas showed significantly higher median SWV than hemorrhagic cysts (4.20 ± 0.42 vs 2.54 ± 1.04 m/s; p 3.81 m/s produced sensitivity 82.1% and specificity 79.2% for differentiation. The paper does not explicitly state additional limitations beyond its predefined inclusion/exclusion criteria, which could limit generalizability to cysts with septations/mural nodules; This paper is centrally about endometriosis — it focuses on using ARFI elastography to distinguish endometriomas from hemorrhagic ovarian cysts.

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Abstract

Purpose To investigate the feasibility of acoustic radiation force impulse imaging in differentiation of endometriomas and hemorrhagic ovarian cysts.

Materials and methods

We evaluated 84 ovarian cysts with high internal echogenicity diagnosed in 70 consecutive women. We excluded simple cysts and hemorrhagic cysts containing septations or mural nodules with detectable flow on Doppler ultrasonography. We obtained the elastographic shear wave velocity (SWV) value of the cysts that could be endometriomas or hemorrhagic ovarian cysts.

Results

Among the 78 ovarian cysts in 70 women without any septation or mural nodule, there were 42 endometriomas and 36 hemorrhagic ovarian cysts. Analysis of median SWV values of the ovarian cysts showed that the endometriomas had considerably higher levels of stiffness compared to the hemorrhagic ovarian cysts [median SWV 4.20 ± 0.42 vs 2.54 ± 1.04 m/s, p < 0.001]. A SWV cutoff value greater than 3.81 m/s yielded sensitivity and specificity values of 82.1 and 79.2 % respectively, for differentiation of endometriomas from hemorrhagic ovarian cysts.

Conclusion

Sonoelastography is a novel imaging technique that enables us to evaluate the stiffness of adnexal lesions. The accurate discrimination of endometriomas and hemorrhagic ovarian cysts is important for avoiding unnecessary surgical procedures. ARFI imaging has a high sensitivity and specificity for distinguishing endometrioma from hemorrhagic ovarian cysts. Similar content being viewed by others

References

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mesh:D004715

MeSH descriptors

Elasticity Imaging Techniques Endometriosis Hemorrhage Ovarian Cysts Ultrasonography, Doppler Adolescent Adult Diagnosis, Differential Elasticity Elasticity Imaging Techniques Endometriosis Female Hemorrhage Humans Middle Aged Ovarian Cysts Prospective Studies ROC Curve Ultrasonography, Doppler Young Adult

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