Relativity of polymorphism of the interleukin-10 gene and endometriosis

Aim To determine whether polymorphism of the interleukin-10(IL-10)gene is associated with endometriosis in a Chinese population.Method 107 women diagnosed with endometriosis by operation were taken as study group,and we sampled their fresh tissue during the operation.We extracted the DNA from the tissue,then used PCR-RFLP to examine the-1082,-819,-592 gene polymorphism in IL-10 gene.Results There was no statistically signigicant difference between the patients and the controls in the frequency of the IL-10-1082,-819,-592 gene polymorphism.Conclusion The frequency of IL-10 gene polymorphism has no statistically significant difference between the patients and the controls.