Adenomyosis and Polycystic Ovary Syndrome in Adolescents and Young Women: More Common Together or Not?

Mustafa Kaplanoğlu, Dilek Kaplanoğlu, Mehmet Alı Sungur
In: Research Square · 2025 · doi:10.21203/rs.3.rs-7282360/v1 · W4414065976
preprint OA: green CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This study compared clinical and ultrasonographic features of adenomyosis and PCOS in young women, finding that HMB, pelvic pain, and dysmenorrhea were more common with adenomyosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This retrospective cross-sectional preprint studied the relationship between adenomyosis and polycystic ovary syndrome (PCOS) in 319 adolescents and young women aged 10–25 years who presented with symptoms suggestive of adenomyosis and/or PCOS, using ultrasonography-based diagnostic criteria (MUSA-revised for adenomyosis) at a single tertiary referral center. Participants were classified as adenomyosis-only (n=29), PCOS-only (n=277), or combined (n=13), and the authors compared clinical and ultrasonographic profiles, finding that BMI was higher in the PCOS group while heavy menstrual bleeding, pelvic pain, and dysmenorrhea were more common in the adenomyosis and combined groups; adenomyosis-associated ultrasound features (e.g., uterine wall asymmetry and junctional zone abnormalities) were also more prevalent. In contrast, Ferriman–Gallwey scores and free androgen index values were higher in the PCOS group, supporting distinct clinical/ultrasound phenotypes even when both conditions co-occur. The paper is limited by its retrospective design, single-center setting, and preprint status (not peer reviewed). This paper is centrally about endometriosis and adenomyosis — it specifically examines adenomyosis and its diagnostic overlap with PCOS in adolescents and young adults, a key adjacent condition frequently discussed alongside endometriosis in pelvic-pain phenotyping.

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Outcome instruments

VAS-pain MUSA

Condition tags

adenomyosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (24)

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