Systemic lupus erythematosus: two patients treated with danazol

Morley KD, K D Morley, Parke A, A Parke, Ann L. Parke, Hughes GR, G R Hughes
British medical journal (Clinical research ed.) · 1982 · vol. 284(6327) , pp. 1431–1432 · doi:10.1136/bmj.284.6327.1431 · PMID:6805552 · PMC1498387 · W2094744093
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Danazol treatment resulted in clinical improvement for two women with systemic lupus erythematosus experiencing premenstrual flaring, highlighting the potential therapeutic value of hormonal regulation.

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Abstract

Two women with systemic lupus erythematosus who showed premenstrual flaring of the disease were treated with danazol, which resulted in clinical improvement.This form of treatment needs to be assessed more widely, as there is little reported evidence that hormonal regulation has therapeutic value in systemic lupus erythematosus.

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MeSH descriptors

Danazol Lupus Erythematosus, Systemic Pregnadienes Adult Danazol Female Humans Lupus Erythematosus, Systemic Menstruation Pregnadienes

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License: CC0 · commercial use OK