Systemic lupus erythematosus: two patients treated with danazol

K.D. Morley, Morley KD, Ann L. Parke, Parke A, G R Hughes, Hughes GR
British medical journal (Clinical research ed.) · 1982 · vol. 284(6327) , pp. 1431–1432 · doi:10.1136/bmj.284.6327.1431 · PMID:6805552 · PMC1498387 · W2094744093
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Danazol treatment resulted in clinical improvement for two women with systemic lupus erythematosus experiencing premenstrual flaring, highlighting the potential therapeutic value of hormonal regulation.

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Abstract

Two women with systemic lupus erythematosus who showed premenstrual flaring of the disease were treated with danazol, which resulted in clinical improvement.This form of treatment needs to be assessed more widely, as there is little reported evidence that hormonal regulation has therapeutic value in systemic lupus erythematosus.

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