THE POTENTIAL EFFECT OF RED DRAGON FRUIT (Hylocereus polyrhizus) PEEL ETHANOL EXTRACT ON ENDOMETRIOSIS PROGRESSIVITY IN ENDOMETRIOSIS MICE

Anindya Hapsari, Yanuar Eka Pujiastutik
In: Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences · 2018 · vol. 12(2) · doi:10.21157/j.ked.hewan.v12i2.10497 · W2901707203
article OA: gold CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-07 ⓘ

Red dragon fruit peel ethanol extract at doses of 0.25, 0.5, and 1 mg/gbw inhibited endometriosis progressivity, indicated by granuloma size, in a mouse model.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-07, 2026-07-13 · read from full text ⓘ

This study evaluated whether red dragon fruit (Hylocereus polyrhizus) peel ethanol extract at doses of 0.25, 0.5, and 1 mg/g body weight affects endometriosis progressivity in a mouse model. Twenty-five female mice were divided into positive control, negative control, and three treatment groups; endometriosis was induced for 14 days, and then placebo or extract was administered orally for the next 14 days while endometriotic lesions were examined, with progressivity assessed by granuloma formation. The authors report significant differences in granuloma among control and treatment groups, leading to the conclusion that the extract could inhibit endometriosis progressivity. This paper is centrally about endometriosis — it tests red dragon fruit peel ethanol extract on granuloma-associated progression in endometriosis mice.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

The aim of this study was to know the effect of red dragon fruit (Hylocereus polyrhizus) peel ethanol extract at dose of 0.25, 0.5, and 1 mg/gbw on endometriosis progressivity, signed by granuloma, on mouse model of endometriosis. Twenty five female mice were used as samples anddivided into 5 groups: 1 positive control, 1 negative control, and 3 treatment groups. Positive control and treatment groups were induced as modelof endometriosis for 14 days. The next 14 days, placebo was given to both control groups, while red dragon fruit peel ethanol extract at dose of0.25, 0.5, and 1 mg/g bw were given to mice in treatment groups as much as 0.2 mL/25 g bw/day orally. Endometriotic lesion was examined.Result showed that there were significantly differences on granuloma among control groups and treatment groups. The conclusion was reddragon fruit peel ethanol extract could inhibit endometriosis progressivity, signed by granuloma, on mouse model of endometriosis.
Full text 1,370 characters · extracted from oa-doi-fallback · 4 sections · click to expand

Abstract

The aim of this study was to know the effect of red dragon fruit (Hylocereus polyrhizus) peel ethanol extract at dose of 0.25, 0.5, and 1 mg/g bw on endometriosis progressivity, signed by granuloma, on mouse model of endometriosis. Twenty five female mice were used as samples and divided into 5 groups: 1 positive control, 1 negative control, and 3 treatment groups. Positive control and treatment groups were induced as model of endometriosis for 14 days. The next 14 days, placebo was given to both control groups, while red dragon fruit peel ethanol extract at dose of 0.25, 0.5, and 1 mg/g bw were given to mice in treatment groups as much as 0.2 mL/25 g bw/day orally. Endometriotic lesion was examined.

Result

showed that there were significantly differences on granuloma among control groups and treatment groups. The conclusion was red dragon fruit peel ethanol extract could inhibit endometriosis progressivity, signed by granuloma, on mouse model of endometriosis.

Keywords

Full Text: PDFDOI: https://doi.org/10.21157/j.ked.hewan.v12i2.10497 Article Metrics

Abstract

view : 0 timesPDF - 0 times Refbacks - There are currently no refbacks. Indexed by: p-ISSN: 1978-225X | e-ISSN: 2502-5600 | Copyright© 2007-2021

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (3)

References (12)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK