Potential Application of Vaporized Drugs via Nasal Inhalers to Prevent Mortality and Central Nervous System Damage Caused by Primary Amoebic Meningoencephalitis Due to Naegleria fowleri.

Siddiqui R; Abouleish MY; Khamis M; Ibrahim T; Khan NA

doi:10.1021/acsptsci.1c00086

Potential Application of Vaporized Drugs via Nasal Inhalers to Prevent Mortality and Central Nervous System Damage Caused by Primary Amoebic Meningoencephalitis Due to Naegleria fowleri.

Siddiqui R, Abouleish MY, Khamis M, Ibrahim T, Khan NA

ACS pharmacology & translational science · 2021 · doi:10.1021/acsptsci.1c00086 · PMID:34151216 · PMC8205233

OA: closed

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Abstract

Here, it is proposed that nasal inhalers with specific anti-Naegleria fowleri drugs or a combination of anti-N. fowleri compounds combined with steroids such as dexamethasone could provide a practical solution for treating primary amoebic meningoencephalitis.

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