ACS pharmacology & translational science

· 8 papers in corpus
2026
doi:10.1021/acsptsci.5c00801 ·PMID:42453334

Diabetes mellitus (DM) represents a heterogeneous group of metabolic disorders characterized by chronic hyperglycemia and progressive metabolic dysregulation, arising from distinct but overlapping pathogenic mechanisms. Emerging evidence po…

2024
doi:10.1021/acsptsci.4c00046 ·PMID:38751624

Glyphosate (GLP) is an active agent of GLP-based herbicides (GBHs), i.e., broad-spectrum and postemergent weedkillers, commercialized by Monsanto as, e.g., Roundup and RangerPro formulants. The GBH crop spraying, dedicated to genetically en…

2023
doi:10.1021/acsptsci.2c00012 ·PMID:37082752

Turmeric (Curcuma longa) has been used for thousands of years for the prevention and treatment of various chronic diseases. Curcumin is just one of >200 ingredients in turmeric. Almost 7000 scientific papers on turmeric and almost 20,000 on…

2022
doi:10.1021/acsptsci.1c00255 ·PMID:35187419

EP2, a G-protein-coupled prostaglandin-E2 receptor, has emerged as a seminal biological target for drug discovery. EP2 receptor activation is typically proinflammatory; therefore, the development of EP2 antagonists to mitigate the severity …

2021
doi:10.1021/acsptsci.1c00086 ·PMID:34151216

Here, it is proposed that nasal inhalers with specific anti-Naegleria fowleri drugs or a combination of anti-N. fowleri compounds combined with steroids such as dexamethasone could provide a practical solution for treating primary amoebic m…

2020
doi:10.1021/acsptsci.0c00132 ·PMID:33344902

Objectives: The purpose of this analysis was to assess, from the patients' perspective, the effectiveness and relative safety of tramadol as an off-label antidepressant and to determine if patients' views and experiences are consistent with…

2019
doi:10.1021/acsptsci.9b00051 ·PMID:32259065

Endothelial cells are the building blocks of the blood vascular system and exhibit well-characterized sexually dimorphic phenotypes with regard to chromosomal and hormonal sex, imparting innate genetic and physiological differences between …

2018
doi:10.1021/acsptsci.8b00038 ·PMID:32219210