Endometriosis of the Colon with Mixed “Germ Cell” Tumor

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AI-generated summary by claude@2026-06, 2026-06-08

A case report describes a woman with endometriosis of the colon that transformed into a mixed germ cell tumor containing yolk sac, choriocarcinoma, and teratoma elements.

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Abstract

A 42-year-old woman was found to have endometriosis of the oviducts. Five years later she had a hysterectomy and oophorectomy, the abnormal findings at this time being endometriosis with a chocolate cyst of one ovary. At a third operation, seven years after the first, she was found to have endometriosis of the colon, associated with malignant tumor in the serosa of the intestine and in the pelvis. Histologically, there was direct transition from benign epithelium in the ectopic endometrial glands, to dysplastic and neoplastic tissue. In different areas, the tumor included elements of yolk sac type (endodermal sinus tumor), choriocarcinoma, and teratoma. The implications of this unique transformation and combination are discussed briefly.

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Condition tags

endometriosis

MeSH descriptors

Colonic Neoplasms Endometriosis Neoplasms, Germ Cell and Embryonal Adult Colonic Neoplasms Colonic Neoplasms Endometriosis Endometriosis Female Humans Metaplasia Middle Aged Neoplasms, Germ Cell and Embryonal Ovarian Neoplasms Ovarian Neoplasms Ovarian Neoplasms

Citation neighborhood

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Cited by (9)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:10:00.881616+00:00
License: CC0 · commercial use OK