News on Adenomyosis

Maria Rosa Maduro
Reproductive sciences (Thousand Oaks, Calif.) · 2018 · vol. 25(4) , pp. 469–470 · doi:10.1177/1933719118764929 · PMID:29554861 · W2791906551
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⚙ AI-generated summary by gemini-2.5-flash-lite+body, 2026-06-13 ⓘ

This review compiles recent research on adenomyosis pathology, molecular characteristics, inflammatory mediators, serum osteopontin, myofibroblast presence, fertility-sparing treatments, and diagnostic imaging.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

“News on Adenomyosis” is a brief editorial-style update in Reproductive Sciences that provides an overview of current themes and referenced work related to adenomyosis, citing multiple studies on adenomyosis pathology, clinical profiles, endometrial transcriptomics, inflammatory mediators, serum biomarkers, tissue microtrauma at the endometrial-myometrium junction, fertility-sparing treatment options, and imaging via transvaginal elastosonography. The piece compiles findings from a range of prior publications rather than presenting original experiments, and the main limitation is that it does not include new data or a detailed methods section. It emphasizes ongoing research directions across molecular mechanisms, diagnostics, and treatment considerations. This paper is centrally about adenomyosis — it is an update that curates and discusses recent research evidence specific to adenomyosis, which is closely related to adenomyosis-related endometrial-myometrial pathology.

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References Bergeron C, Amant F, Ferenczy A. Pathology and physiopathology of adenomyosis. Best Pract Res Clin Obstet Gynaecol. 2006;20: 511–521. Li X, Liu X, Guo SW. Clinical profiles of 710 premenopausal women with adenomyosis who underwent hysterectomy. J Obstet Gynaecol Res. 2014;40:485–494. Herndon CN, Aghajanova L, Balayan S, et al. Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis. Reprod Sci. 2016;23(10):1289–1303. Yen CF, Huang SJ, Lee CL, et al. Molecular Characteristics of the Endometrium in Uterine Adenomyosis and Its Biochemical Microenvironment. Reprod Sci. 2017;24(10):1346–1361. Carrarelli P, Yen CF, Funghi L, et al. Expression of Inflammatory and Neurogenic Mediators in Adenomyosis. A Pathogenetic Role. Reprod Sci. 2017;24(3):369–375. Streuli I, Santulli P, Chouzenoux S, et al. Serum Osteopontin Levels Are Decreased in Focal Adenomyosis. Reprod Sci. 2017;24(5):773–782. Ibrahim MG, Sillem M, Plendl J, et al. Myofibroblasts Are Evidence of Chronic Tissue Microtrauma at the Endometrial-Myome-trial Junctional Zone in Uteri With Adenomyosis. Reprod Sci. 2017;24(10):1410–1418. Rocha TP, Andres MP, Borrelli GM, et al. Fertility-Sparing Treatment of Adenomyosis in Patients With Infertility: A Systematic Review of Current Options. Reprod Sci. 2018;25(4):480–486. Liu X, Ding D, Ren Y, et al. Transvaginal Elastosonography as an Imaging Technique for Diagnosing Adenomyosis. Reprod Sci. 2018;25(4):498–514. Rights and permissions About this article Cite this article Maduro, M.R. News on Adenomyosis. Reprod. Sci. 25, 469–470 (2018). https://doi.org/10.1177/1933719118764929 Published: Version of record: Issue date: DOI: https://doi.org/10.1177/1933719118764929

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Infertility Female Fertility Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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