Extraovarian Endometrioid Carcinoma: Review of the Literature and Report of Two Cases with Unusual Features

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AI-generated summary by claude@2026-06, 2026-06-08

This review reports two cases of extraovarian endometrioid carcinoma discovered years after hysterectomy and oophorectomy, highlighting the need to examine endometriosis for atypical changes that may predict malignancy.

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Abstract

Two cases of extraovarian endometrioid carcinoma are reported. The patients had had total hysterectomies and bilateral salpingo-oophorectomies 17 and 7 years before discovery of the endometrioid tumors. The ovaries in both cases contained endometriosis with adenomatous or atypical changes. Endometriosis should be routinely examined for hyperplastic or atypical features, as these may be significant harbingers of ovarian or extraovarian endometrioid carcinoma. Progestogen therapy for endometrioid neoplasm is theoretically promising, but has yet to be systematically investigated.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometriosis Vaginal Neoplasms Adenocarcinoma Adenocarcinoma Aged Endometriosis Endometriosis Female Humans Hysterectomy Middle Aged Ovarian Neoplasms Ovarian Neoplasms Vaginal Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (14)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-14T05:58:53.789372+00:00
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