Minimal and mild endometriosis. Nd:YAG laser treatment and changes in prostaglandin concentrations in peritoneal fluid.
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Nd:YAG laser treatment for minimal and mild endometriosis reduced peritoneal fluid prostaglandin levels and was followed by pregnancy in 30 of 52 patients within one year.
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Abstract
Among many patients, infertility originates with minimal and mild endometriosis. Recently, peritoneal fluid factors have come to be associated with infertility in minimal and mild endometriosis patients, and prostaglandin (PG) is suspected of being one of those factors. We use the Nd:YAG laser for treatment of endometriosis; a total of 52 cases of minimal and mild endometriosis have been treated so far with the laser under laparoscopy in our clinic. At the same time we measured the peritoneal fluid volume and PG concentration in peritoneal fluid. Peritoneal fluid volume and PGE2 concentrations were found to be significantly higher than those in the control group (tubal obstruction patients). Seven of 52 patients received second-look laparoscopy three months after Nd:YAG laser treatment; the PG concentration showed a tendency to decrease in many patients, and the PGE2 concentration turned out to be insignificant. Within one year, 30 patients achieved pregnancy. In minimal and mild endometriosis patients Nd:YAG laser treatment may alter the PG concentration in peritoneal fluid, thereby increasing the change of pregnancy.
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Cited by (8)
- Gastrointestinal Myoelectrical Activity (GIMA) Biomarker for Noninvasive Diagnosis of Endometriosis 2024
- Gastrointestinal Myoelectrical Activity (GIMA) Biomarker for Noninvasive Diagnosis of Endometriosis 2024
- Neuroendocrine–immune disequilibrium and endometriosis: an interdisciplinary approach 2007
- "Endometriose do trato gastrointestinal: correlações clínicas e laparoscópicas; papel da corrida dos órgãos peritoneais na endometriose (COPE)" 2005
- Pathogenesis of Endometriosis: The Role of Peritoneal Fluid 1999
- Relation of endometriosis and neuromuscular disease of the gastrointestinal tract: new insights 1998
- Endometriotic disease: the role of peritoneal fluid 1998
- Decrease in Peripheral Blood Polymorphonuclear Leukocyte Chemotactic Index in Endometriosis: Role of Prostaglandin E2 Release 1998
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chemicals 2
prostaglandin
prostaglandin
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