Fertility preservation after caesarean delivery in a woman diagnosed with Morbus Hodgkin disease during pregnancy

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This case report describes a primigravida woman who underwent fertility preservation techniques shortly after caesarean delivery following a new diagnosis of Hodgkin disease during pregnancy.

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This case report describes a primigravida woman who was diagnosed with Hodgkin’s lymphoma during pregnancy and underwent fertility preservation techniques shortly after delivering via caesarean section. The authors detail the clinical management of combining ovarian tissue cryopreservation with immediate postpartum treatment planning for cancer therapy. The paper serves as a proof of principle for preserving reproductive potential in women facing hematological malignancies diagnosed while pregnant. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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References

Von Wolff M et al. Fertility preservation in women: a practical guide to preservation techniques and therapeutic strategies in breast cancer. Hodgkin’s lymphoma and borderline ovarian tumours by the fertility preservation network FertiPROTEKT. Arch Gynecol Obstet. 2011;284(2):427–35. Diehl V et al. Hodgkin’s lymphoma: biology and treatment strategies for primary, refractory, and relapsed disease. Hematology Am Soc Hematol Educ Program. 2003;2003:225–47. Behringer K et al. Secondary amenorrhea after Hodgkin’s lymphoma is influenced by age at treatment, stage of disease, chemotherapy regimen, and the use of oral contraceptives during therapy: a report from the German Hodgkin’s Lymphoma Study Group. J Clin Oncol. 2005;23(30):7555–64. Meirow D. Reproduction post-chemotherapy in young cancer patients. Mol Cell Endocrinol. 2000;169(1–2):123–31. Brenner B, Avivi I, Lishner M. Haematological cancers in pregnancy. Lancet. 2012;379(9815):580–7. Isachenko V et al. Cryobanking of human ovarian tissue for anti-cancer treatment: comparison of vitrification and conventional freezing. Cryo Lett. 2009;30:449–54. Dolmans MM et al. Risk of transferring malignant cells with transplanted frozen-thawed ovarian tissue. Fertil Steril. 2013;99(6):1514–22. Kahraman K et al. Microdose gonadotropin-releasing hormone agonist flare-up protocol versus multiple dose gonadotropin-releasing hormone antagonist protocol in poor responders undergoing intracytoplasmic sperm injection-embryo transfer cycle. Fertil Steril. 2009;91(6):2437–44. Loren AW et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol. 2013;31(19):2500–10. Bedoschi GM et al. Ovarian stimulation during the luteal phase for fertility preservation of cancer patients: case reports and review of the literature. J Assist Reprod Genet. 2010;27(8):491–4.

Acknowledgement

None. Author information Authors and Affiliations Corresponding author Additional information Capsule The combination of fertility preservation techniques shortly after delivery. A case report of a primigravida woman with a newly diagnosed Morbus Hodgkin disease and a proof of principle. Rights and permissions About this article Cite this article Gundelach, T., Stuck, D., Widschwendter, P. et al. Fertility preservation after caesarean delivery in a woman diagnosed with Morbus Hodgkin disease during pregnancy. J Assist Reprod Genet 31, 51–53 (2014). https://doi.org/10.1007/s10815-013-0126-7 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s10815-013-0126-7

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MeSH descriptors

Cesarean Section Fertility Preservation Hodgkin Disease Pregnancy Complications, Neoplastic Adult Female Hodgkin Disease Hodgkin Disease Humans Ovulation Induction Postpartum Period Pregnancy Pregnancy Complications, Neoplastic Pregnancy Complications, Neoplastic Pregnancy Trimester, Third

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