PREGNANCY COMPLICATIONS IN PATIENTS WITH ENDOMETRIOSIS

Endometriosis is a chronic disease, which causes infertility in 40%. In case of ineffective therapy, assisted reproductive technology is indicated. Endometriosis is an independent risk factor for mother and fetus morbidities. Prenatal monitoring, is essential in prevention of pregnancy-related complications.

Evaluation and comparison the frequency of pregnancy complications in women with endometriosis after traditional treatment methods of infertility and after IVF.

Retrospective study included 320 patients aged 28-46, with different locations of endometriosis, diagnosed by laparoscopy. The patients were divided into two groups: I group – 170 pregnant women using the fertility treatment method – IVF and II group – 150 pregnant women conceived naturally. Pregnancy complications were evaluated and statistically analyzed.

In pregnant women with endometriosis after IVF treatment the most common pregnancy complication was caesarian section - 79.4%, both emergency and elective. The frequency of preeclampsia was also high - 54.7%. The preterm birth occurred in 49.4%, the same trend was revealed in the II group - 52, 0%. Placenta previa and placenta abruption were rare in both groups 10.6% vs. 4.0% and 3.5% vs. 2%. In general, the adverse pregnancy outcome in the ART group was significantly higher compared to pregnant women conceived naturally except for the preterm delivery and abruption of the placenta.

IVF pregnancy in patients with endometriosis should be considered a high-risk pregnancy regarding adverse outcomes: cesarean section, preeclampsia and preterm delivery. However, these pregnancy complications should be linked to the endometriosis and infertility and may not to the ART. Downloads

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