Transcervical endometrial cryoablation (ECA) for menorrhagia

R Pittrof, Rüdiger Pittrof, Shamim S. Majid, S Majid, Amanda Murray, A Murray
International Journal of Gynecology & Obstetrics · 1994 · vol. 47(2) , pp. 135–140 · doi:10.1016/0020-7292(94)90353-0 · PMID:7843482 · W2048531659
Non-randomised trial OA: closed CC0 ⤵ 6 in-corpus citations
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This prospective study of 67 women found transcervical endometrial cryoablation (ECA) to be technically easy, complication-free, and improved menstrual symptoms in 63% of patients with menorrhagia.

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Abstract

OBJECTIVE: To evaluate endometrial cryoablation (ECA) as a treatment for menorrhagia. METHOD: Prospective study of 67 women. ECA uses the Joule Thompson principle of expanding gases. The ECA probe has a channel to inject saline solution into the uterine cavity. The probe is introduced into the uterine cavity, which is distended with 5 ml saline solution. The device is activated for two freeze-thaw cycles. The saline solution forms an ice mold of the uterine cavity which can be observed by ultrasound scan. RESULTS: No surgical or long-term complications were observed. Two-thirds of patients followed up for > 3 months were completely satisfied. CONCLUSIONS: ECA is technically very easy, can be learned quickly, is free of complications and led to improvement of menstrual symptoms in 63% of patients followed up for 3-18 months. The device is virtually maintenance-free and requires only a small initial investment, while running costs are negligible.

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MeSH descriptors

Cryosurgery Endometrium Menorrhagia Adult Costs and Cost Analysis Cryosurgery Cryosurgery Endometrium Female Follow-Up Studies Humans Hysterectomy Menorrhagia Menorrhagia Patient Satisfaction Prospective Studies Sodium Chloride Time Factors Treatment Failure

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