Sulpiride(Dogmatyl®)によるEndometriosisの治療
Sulpiride was administered to 15 endometriosis patients to induce amenorrhea and anovulation, resulting in symptom improvement in most and one pregnancy.
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本研究は、ホルモン剤以外であるsulpiride(Dogmatyl®)を用いて高プロラクチン血症を誘発し、無排卵もしくは無月経を起こすことで子宮内膜症患者15例を治療した成績を検討した。sulpirideを100〜300mg/日で90〜120日間経口投与し、無月経は10例(66.7%)、無排卵は12例(80%)で認められ、血中PRLは用量・期間に関係なく約200ng/mlで推移した。無排卵例ではLHサージが認められ、E2は初期卵胞期相当、Pは低値で無排卵が確認され、月経痛を伴う13例中10例(76.9%)で症状の著明な改善が報告された一方、挙児希望14例では治療後妊娠は1例のみであった。This paper is centrally about endometriosis — sulpirideによる高プロラクチン血症誘発を介した無排卵・無月経による子宮内膜症治療成績を報告している。
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- ENDOMETRIOSIS AND INFERTILITY via openalex
- Experiences with Danazol (an antigonadotropin) in the treatment of infertility via openalex
- W2118673349 via openalex
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