Microbial Transformation of Danazol

M. Iqbal Choudhary, Azizuddin, Atta‐ur Rahman
In: Natural Product Letters · 2002 · vol. 16(2) , pp. 101–106 · doi:10.1080/10575630290019994 · PMID:11990425 · W2044953508
article OA: closed CC0 ⤵ 3 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Fermentation of danazol with *Fusarium lini*, *Aspergillus niger*, and *Cephalosporium aphidicola* yielded two hydroxylated derivatives, while *Bacillus cerus* yielded only one.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Danazol (17beta-hydroxy-17alpha-pregna-2,4-dien-20-yno-[2,3-d] isoxazole) (1) on fermentation with Fusarium lini, Aspergillus niger, and Cephalosporium aphidicola yielded 17beta-hydroxy-2-(hydroxymethyl)-17-alpha-pregn-4-en-20-yn-3-one (2) and 17beta-hydroxy-2-(hydroxymethyl)-17 alpha-pregna-1,4-dien-20-yn-3-one (3), while the fermentation of 1 with Bacillus cerus yielded compound 2 only.

My notes (saved in your browser only)

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (3)

References (1)

Cited by (3)

Source provenance

openalex
last seen: 2026-05-10T11:25:12.659626+00:00
License: CC0 · commercial use OK