Müllerian adenosarcoma with ovarian sex cord-like differentiation. A light- and electron-microscopic study

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This light- and electron-microscopic study describes a rare Müllerian adenosarcoma in the uterine cervix with neoplastic glands and a sarcomatous stroma showing ovarian sex-cord-like differentiation.

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Abstract

A Müllerian adenosarcoma in which the sarcomatous element showed ovarian sex-cord like differentiation, occurred as a polypoid growth in the uterine cervix of a 53-year-old woman. The tumor was composed of an admixture of benign neoplastic glands and a sarcomatous stroma, the latter containing in addition to endometrial stromal sarcoma, nests of lipid-rich cells resembling ovarian sex-cord elements. This is the first report of such differentiation in Müllerian adenosarcoma. Origin from a focus of cervical endometriosis is postulated.

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Condition tags

endometriosis

MeSH descriptors

Mullerian Ducts Ovary Uterine Neoplasms Wilms Tumor Cell Differentiation Female Foam Cells Foam Cells Humans Hysterectomy Lymph Node Excision Middle Aged Ovary Polyps Polyps Uterine Neoplasms Uterine Neoplasms Wilms Tumor Wilms Tumor

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Source provenance

europepmc
last seen: 2026-08-15T06:15:18.721777+00:00
pubmed
last seen: 2026-05-13T22:09:40.384591+00:00
unpaywall
last seen: 2026-08-15T06:29:46.044917+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine