Piroxicam-β-Cyclodextrin in the Treatment of Dysmenorrhoea

Summary Piroxicam-β-cyclodextrin has been shown to be significantly more effective than placebo in the relief of menstrual pain and the somatic symptoms associated with dysmenorrhoea. In comparative studies with naproxen and ketoprofen, piroxicam-β-cyclodextrin was shown to produce an earlier onset of pain relief with a longer lasting effect. Tolerability with piroxicam-β-cyclodextrin was good, with few side effects being reported. The efficacy and tolerability of piroxicam-β-cyclodextrin make it well qualified for use as first-line therapy for primary dysmenorrhoea in patients in whom oral contraception is not required or who are unable to tolerate estrogenic and progestational agents. Similar content being viewed by others References Akerlund M, Anderson K.E, Ingermarsson I. Effects of terbutaline on myometrial activity, uterine blood flow, and lower abdominal pain in women with primary dysmenorrhoea. British Journal of Obstetrics and Gynaecology 83: 673–678, 1976 Bergsjo P. 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Giornale Italiano di Ostetricia e Ginecologia 8: 679–687, 1986 Author information Authors and Affiliations Rights and permissions About this article Cite this article Costa, S., Zinelli, G. & Bufalino, L. Piroxicam-β-Cyclodextrin in the Treatment of Dysmenorrhoea. Drug Invest 2 (Suppl 4), 73–78 (1990). https://doi.org/10.1007/BF03258231 Published: Issue date: DOI: https://doi.org/10.1007/BF03258231