Endometriosis and Genital Anomalies: Some Histogenetic Aspects of External Endometriosis

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This study identified six cases of endometriosis co-occurring with genital anomalies, exploring histogenetic mechanisms beyond simple transplantation to include celomic metaplasia, müllerian remnants, and genetic, immunologic, and hormonal factors.

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Abstract

Six cases with a coexistence of endometriosis and genital anomalies among 112 patients with external endometriosis and 90 patients with genital anomaly were detected. Three cases of severe endometriosis associated with uterovaginal duplication, unilateral renal agenesis and ipsilateral blind vagina and the latter in a patient with Rokitansky-Kuster-Hauser syndrome are presented. Another case with obstructive genital anomaly without endometriosis is also presented. The histogenetic mechanisms of endometriosis are discussed. The transplantation theory is not sufficient to explain all the cases and, therefore, the theory of celomic metaplasia and the theory of müllerian remains or Cullen's theory, as well as the intervention of genetic-constitutional, immunologic, hormonal and other factors must also be considered.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Genitalia, Female Genital Neoplasms, Female Adolescent Adult Endometriosis Endometriosis Female Genitalia, Female Genitalia, Female Genital Neoplasms, Female Genital Neoplasms, Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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europepmc
last seen: 2026-10-01T06:15:55.914501+00:00
openalex
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pubmed
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License: CC0 · commercial use OK