Patologie mestruali e contraccezione: principi di personalizzazione della scelta terapeutica
Hormonal contraceptives, including short-acting and long-acting methods, offer treatment options for menstrual disorders by managing cycle alterations and related conditions, with personalized choice based on hormone combinations, dosages, and contraindications.
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This narrative review discusses menstrual pathologies, including dysfunctional/disendocrine cycle disorders (e.g., rhythm, duration, quantity abnormalities and dysmenorrhea) and extra-uterine conditions with catamenial exacerbation, and outlines how hormonal contraception can be used as a therapeutic option. Drawing on prevalence data and high-level clinical classification frameworks (including FIGO PALM-COEIN), the authors summarize that menstrual disorders are common, dysmenorrhea is often underreported and undertreated, and catamenial worsening is linked to immune hyperreactivity (with mast cell degranulation in response to falling estradiol and progesterone). A key limitation is that, as a review/rassagna rather than a primary study, it provides an overview and does not evaluate patient-level efficacy or safety outcomes of specific contraceptive regimens. Relevance to endometriosis: the paper is included because it discusses catamenial exacerbation of inflammatory and autoimmune conditions—an area often connected to endometriosis-related pelvic pain—though it does not specifically center endometriosis or adenomyosis.
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