A rare case of appendicular endometriosis mimicking appendicitis: a case report

Arad Abadi, Usra I Ghanem, Layan Melhem, Osama Mallah, Ahmad Hodali
In: Research Connections · 2026 · vol. 1(2) · doi:10.1093/rescon/vmag041 · W7153718318
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This case report describes a 23-year-old female whose appendicular endometriosis was surgically confirmed via appendectomy after mimicking appendicitis symptoms and showing inconclusive imaging.

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Abstract

Abstract Introduction Appendicular endometriosis is a rare condition accounting for 1%–3% of all intestinal endometriosis. The presentation of appendicular endometriosis is often nonspecific and may mimic appendicitis. Case Description A 23-year-old female presented with colicky lower abdominal pain, dysuria, and menstrual cyclic pain. Clinical examination and imaging, including ultrasound and CT scan, were inconclusive. Due to persistent symptoms and to exclude a focal appendiceal lesion, a laparoscopic appendectomy was performed. Intraoperative findings revealed a firm, dilated appendicular tip without signs of inflammation. Histopathological analysis confirmed appendicular endometriosis with endometrial glands, characterized by the presence of both endometrial glands and stroma, with immunoreactivity for CD10 in the stromal cells. The patient recovered postoperatively, and the pain has resolved. Discussion Appendicular endometriosis is diagnostically challenging. While laparoscopy is a primary tool for visualizing pelvic and appendiceal abnormalities, definitive diagnosis rests on detailed histopathological confirmation. This case highlights the diagnostic process of appendicular endometriosis and recommends including it as part of the differential diagnosis of acute lower abdominal pain. Learning points

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Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (9)

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last seen: 2026-07-01T06:05:52.148367+00:00
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