Successful Medical Treatment With Danazol After Failed Embolization of Uterine Arteriovenous Malformation
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Danazol successfully resolved a uterine arteriovenous malformation after failed embolization, demonstrating potential for medical management in hemodynamically stable patients.
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Abstract
In Brief BACKGROUND Transcatheter arterial embolization has been the therapy of choice for uterine arteriovenous malformations, whereas medical therapy has not been popular because of patient propensity to bleed. CASE A 29-year-old woman, gravida 3, para 0, was diagnosed with uterine arteriovenous malformation. Because initial treatment with uterine artery embolization was unsuccessful, she was ultimately treated with danazol. Resolution of the lesion after 2 weeks of danazol therapy was observed. As of follow-up at 16 months, she has remained free from further abnormal bleeding episodes and recurrence of the lesion. CONCLUSION Danazol has the potential for medical management of uterine arteriovenous malformations in hemodynamically stable patients who do not respond to embolization. Danazol has the potential for medical management of uterine arteriovenous malformation in hemodynamically stable patients who do not respond to embolization.
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Too few in-corpus citations on either side for a chart; here are the lists.
Cites (2)
- Endometrial thickness, morphology, vascular penetration and velocimetry in predicting implantation in an <i>in vitro</i> fertilization program 1995
- Altered uterine artery blood flow impedance after danazol therapy: possible mode of action in dysfunctional uterine bleeding 1999
Cited by (3)
- Medical treatment of uterine arteriovenous malformation: a systematic review and meta-analysis 2021
- A case of severe uterine arteriovenous malformation treated with danazol followed by a transarterial embolization of unilateral uterine and ovarian arteries 2015
- Danazol as a Treatment for Uterine Arteriovenous Malformation: A Case Report 2023
References (6)
- Altered uterine artery blood flow impedance after danazol therapy: possible mode of action in dysfunctional uterine bleeding via openalex
- Endometrial thickness, morphology, vascular penetration and velocimetry in predicting implantation in an <i>in vitro</i> fertilization program via openalex
- doi:10.1097/00006254-199712000-00004 via openalex
- doi:10.1016/s0015-0282(01)02900-4 via openalex
- doi:10.1148/radiology.206.1.9423660 via openalex
- doi:10.1016/0029-7844(96)00122-6 via openalex
Cited by (3)
- Danazol as a Treatment for Uterine Arteriovenous Malformation: A Case Report 2023
- Medical treatment of uterine arteriovenous malformation: a systematic review and meta-analysis 2021
- A case of severe uterine arteriovenous malformation treated with danazol followed by a transarterial embolization of unilateral uterine and ovarian arteries 2015
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